UCSF

PI4-kinase Beta Subunit, Human (96 Compounds)

Swissprot:
PI4KB_HUMAN
Stitch:
PI4KB_HUMAN
UniProt:
Q9UBF8
ChEMBL:
CHEMBL3268
Reactome:
REACT_120836
PDB:
PI4KB

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 96 14 5 4
Binding ≤ 1μM 12 3 0 3

Reactome Network (1)

Reactome ID Description Species
REACT_120836 Synthesis of PIPs at the Golgi membrane Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
P3C2A_HUMAN O00443 CHEMBL1075102 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Subunit Alpha, Human 3
P4K2A_HUMAN Q9BTU6 CHEMBL2251 PI4-kinase Type II, Human 13
P4K2B_HUMAN Q8TCG2 CHEMBL3220 PI4-kinase Type II Beta, Human 13
PI4KA_HUMAN P42356 CHEMBL3667 PI4-kinase Alpha Subunit, Human 13
PK3C3_HUMAN Q8NEB9 CHEMBL1075165 Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, Human 3

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PI4KB-1-E PI4-kinase Beta Subunit (cluster #1 Of 2), Eukaryotic 95 13 4 4
PI4KB-2-E PI4-kinase Beta Subunit (cluster #2 Of 2), Eukaryotic 1 1 1 0
Uniprot Swissprot Chembl Description Number Shared
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 77
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 77
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 77
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 75
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 75
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 73
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 69
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 65
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 61
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 59
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 58
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 57
P4K2A_HUMAN Q9BTU6 CHEMBL2251 PI4-kinase Type II, Human 13
P4K2B_HUMAN Q8TCG2 CHEMBL3220 PI4-kinase Type II Beta, Human 13
PI4KA_HUMAN P42356 CHEMBL3667 PI4-kinase Alpha Subunit, Human 13
P3C2B_HUMAN O00750 CHEMBL5554 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Beta Polypeptide, Human 5
Q9BJF5_TOXGO Q9BJF5 CHEMBL1781862 Calmodulin-domain Protein Kinase 1, Toxgo 5
MTOR_MOUSE Q9JLN9 CHEMBL1255165 Serine/threonine-protein Kinase MTOR, Mouse 3
P3C2A_HUMAN O00443 CHEMBL1075102 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Subunit Alpha, Human 3
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 3
PK3C3_HUMAN Q8NEB9 CHEMBL1075165 Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, Human 3
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 2
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 2
CLK3_HUMAN P49761 CHEMBL4226 Dual Specificity Protein Kinase CLK3, Human 2
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 2
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 2
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 2
PI42C_HUMAN Q8TBX8 CHEMBL1770034 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Gamma, Human 2
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 1
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 1
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 1
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 1
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 1
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 1
NLK_HUMAN Q9UBE8 CHEMBL5364 Serine/threonine Protein Kinase NLK, Human 1
NOS1_HUMAN P29475 CHEMBL3568 Nitric-oxide Synthase, Brain, Human 1
NOS1_RAT P29476 CHEMBL3048 Nitric-oxide Synthase, Brain, Rat 1
NOS2_HUMAN P35228 CHEMBL4481 Nitric Oxide Synthase, Inducible, Human 1
NOS3_HUMAN P29474 CHEMBL4803 Nitric-oxide Synthase, Endothelial, Human 1
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 1

Most Common Rings