ZINC 12

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Names
Compounds (251)
Reactome (0)
Related By:
Pathway (0)
Organism (2)
Gene (2)
Org. Clust. (6)
ChEMBL (20)
Rings (6)

Nitric-oxide Synthase, Brain, Rat (251 Compounds)

Swissprot:: NOS1_RAT
Stitch:: NOS1_RAT
UniProt:: P29476
ChEMBL:: CHEMBL3048
PDB:: 1B8Q (DOCK); 1CMI (DOCK); 1F20 (DOCK); 1K2R (DOCK); 1K2S (DOCK); 1K2T (DOCK); 1K2U (DOCK); 1LZX (DOCK); 1LZZ (DOCK); 1M00 (DOCK); 1MMV (DOCK); 1MMW (DOCK); 1OM4 (DOCK); 1OM5 (DOCK); 1P6H (DOCK); 1P6I (DOCK); 1P6J (DOCK); 1P6K (DOCK); 1QAU (DOCK); 1QAV (DOCK); 1QW6 (DOCK); 1QWC (DOCK); 1RS6 (DOCK); 1RS7 (DOCK); 1TLL (DOCK); 1VAG (DOCK); 1ZVI (DOCK); 1ZVL (DOCK); 1ZZQ (DOCK); 1ZZR (DOCK); 1ZZU (DOCK); 2G6H (DOCK); 2G6I (DOCK); 2G6J (DOCK); 2G6K (DOCK); 2G6L (DOCK); 2G6M (DOCK); 2G6N (DOCK); 2HX3 (DOCK); 2HX4 (DOCK); 3B3M (DOCK); 3B3N (DOCK); 3B3O (DOCK); 3B3P (DOCK); 3DQR (DOCK); 3FC5 (DOCK); 3HSN (DOCK); 3HSO (DOCK); 3HSP (DOCK); 3JT3 (DOCK); 3JT4 (DOCK); 3JT5 (DOCK); 3JT6 (DOCK); 3JT7 (DOCK); 3JT8 (DOCK); 3JT9 (DOCK); 3JTA (DOCK); 3JWS (DOCK); 3JWT (DOCK); 3JWU (DOCK); 3JWV (DOCK); 3JX0 (DOCK); 3JX1 (DOCK); 3JX2 (DOCK); 3JX3 (DOCK); 3JX4 (DOCK); 3JX5 (DOCK); 3JX6 (DOCK); 3N2R (DOCK); 3N5V (DOCK); 3N5W (DOCK); 3N5X (DOCK); 3N5Y (DOCK); 3N5Z (DOCK); 3N60 (DOCK); 3N61 (DOCK); 3N62 (DOCK); 3N63 (DOCK); 3N64 (DOCK); 3N65 (DOCK); 3N66 (DOCK); 3N67 (DOCK); 3N68 (DOCK); 3N69 (DOCK); 3N6A (DOCK); 3N6B (DOCK); 3N6C (DOCK); 3N6D (DOCK); 3N6E (DOCK); 3N6F (DOCK); 3N6G (DOCK); 3NLJ (DOCK); 3NLK (DOCK); 3NLM (DOCK); 3NLN (DOCK); 3NLO (DOCK); 3NLP (DOCK); 3NLQ (DOCK); 3NLR (DOCK); 3NLV (DOCK); 3NLW (DOCK); 3NLX (DOCK); 3NLY (DOCK); 3NLZ (DOCK); 3NM0 (DOCK); 3NNY (DOCK); 3NNZ (DOCK); 3PNE (DOCK); 3PNF (DOCK); 3PNG (DOCK); 3Q99 (DOCK); 3Q9A (DOCK); 3SVP (DOCK); 3SVQ (DOCK); Nos1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	251	27	7	12
Binding ≤ 1μM	156	12	3	9
Functional ≤ 10μM	55	6	2	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
NOS1_HUMAN	P29475	CHEMBL3568	Nitric-oxide Synthase, Brain, Human	645	79	16	31
NOS1_MOUSE	Q9Z0J4	CHEMBL4719	Nitric-oxide Synthase, Brain, Mouse	27	4	2	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
NOS2_RAT	Q06518	CHEMBL3051	Nitric Oxide Synthase, Inducible, Rat	2	2	2	2
NOS3_RAT	Q62600	CHEMBL1075230	Nitric Oxide Synthase, Endothelial, Rat	5	0	0	0

Clustered By Gene (0)

Clustered By Organism (6)

Code	Description	Substances	Purchasable	Natural	In Man
NOS1-1-E	Nitric-oxide Synthase, Brain (cluster #1 Of 7), Eukaryotic	381	16	1	13
NOS1-2-E	Nitric-oxide Synthase, Brain (cluster #2 Of 7), Eukaryotic	114	16	9	13
NOS1-3-E	Nitric-oxide Synthase, Brain (cluster #3 Of 7), Eukaryotic	94	28	2	10
NOS1-4-E	Nitric-oxide Synthase, Brain (cluster #4 Of 7), Eukaryotic	170	14	2	1
NOS1-5-E	Nitric-oxide Synthase, Brain (cluster #5 Of 7), Eukaryotic	46	16	4	0
NOS1-6-E	Nitric-oxide Synthase, Brain (cluster #6 Of 7), Eukaryotic	10	1	0	1
NOS1-7-E	Nitric-oxide Synthase, Brain (cluster #7 Of 7), Eukaryotic	7	4	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
NOS1_HUMAN	P29475	CHEMBL3568	Nitric-oxide Synthase, Brain, Human	124
NOS2_HUMAN	P35228	CHEMBL4481	Nitric Oxide Synthase, Inducible, Human	87
NOS3_HUMAN	P29474	CHEMBL4803	Nitric-oxide Synthase, Endothelial, Human	80
NOS2_MOUSE	P29477	CHEMBL3464	Nitric Oxide Synthase, Inducible, Mouse	64
NOS3_BOVIN	P29473	CHEMBL4802	Nitric-oxide Synthase, Endothelial, Bovin	34
Z80120	Z80120	CHEMBL614285	DLD-1 (Colon Adenocarcinoma Cells)	11
NOS3_RAT	Q62600	CHEMBL1075230	Nitric Oxide Synthase, Endothelial, Rat	5
NOS1_MOUSE	Q9Z0J4	CHEMBL4719	Nitric-oxide Synthase, Brain, Mouse	2
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	1
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	1
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	1
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	1
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	1
NOS3_MOUSE	P70313	CHEMBL2643	Nitric-oxide Synthase, Endothelial, Mouse	1
P4K2A_HUMAN	Q9BTU6	CHEMBL2251	PI4-kinase Type II, Human	1
P4K2B_HUMAN	Q8TCG2	CHEMBL3220	PI4-kinase Type II Beta, Human	1
PI4KA_HUMAN	P42356	CHEMBL3667	PI4-kinase Alpha Subunit, Human	1
PI4KB_HUMAN	Q9UBF8	CHEMBL3268	PI4-kinase Beta Subunit, Human	1
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	1
Z80418	Z80418	CHEMBL612557	RAW264.7 (Monocytic-macrophage Leukemia Cells)	1