| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 645 | 79 | 16 | 31 |
| Binding ≤ 1μM | 371 | 48 | 11 | 22 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_23862 | Nitric oxide stimulates guanylate cyclase | Homo sapiens |
| REACT_121256 | Phagosomal maturation (early endosomal stage) | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| NOS2_HUMAN | P35228 | CHEMBL4481 | Nitric Oxide Synthase, Inducible, Human | 375 |
| NOS3_HUMAN | P29474 | CHEMBL4803 | Nitric-oxide Synthase, Endothelial, Human | 274 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| NOS2_HUMAN | P35228 | CHEMBL4481 | Nitric Oxide Synthase, Inducible, Human | 375 |
| NOS3_HUMAN | P29474 | CHEMBL4803 | Nitric-oxide Synthase, Endothelial, Human | 274 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| NOS1_MOUSE | Q9Z0J4 | CHEMBL4719 | Nitric-oxide Synthase, Brain, Mouse | 27 | 4 | 2 | 2 |
| NOS1_RAT | P29476 | CHEMBL3048 | Nitric-oxide Synthase, Brain, Rat | 251 | 27 | 7 | 12 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| NOS2_HUMAN | P35228 | CHEMBL4481 | Nitric Oxide Synthase, Inducible, Human | 702 | 81 | 18 | 26 |
| NOS3_HUMAN | P29474 | CHEMBL4803 | Nitric-oxide Synthase, Endothelial, Human | 302 | 50 | 14 | 18 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| NOS1-1-E | Nitric-oxide Synthase, Brain (cluster #1 Of 7), Eukaryotic | 381 | 16 | 1 | 13 |
| NOS1-2-E | Nitric-oxide Synthase, Brain (cluster #2 Of 7), Eukaryotic | 114 | 16 | 9 | 13 |
| NOS1-3-E | Nitric-oxide Synthase, Brain (cluster #3 Of 7), Eukaryotic | 94 | 28 | 2 | 10 |
| NOS1-4-E | Nitric-oxide Synthase, Brain (cluster #4 Of 7), Eukaryotic | 170 | 14 | 2 | 1 |
| NOS1-5-E | Nitric-oxide Synthase, Brain (cluster #5 Of 7), Eukaryotic | 46 | 16 | 4 | 0 |
| NOS1-6-E | Nitric-oxide Synthase, Brain (cluster #6 Of 7), Eukaryotic | 10 | 1 | 0 | 1 |
| NOS1-7-E | Nitric-oxide Synthase, Brain (cluster #7 Of 7), Eukaryotic | 7 | 4 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| NOS2_HUMAN | P35228 | CHEMBL4481 | Nitric Oxide Synthase, Inducible, Human | 375 |
| NOS3_HUMAN | P29474 | CHEMBL4803 | Nitric-oxide Synthase, Endothelial, Human | 274 |
| NOS1_RAT | P29476 | CHEMBL3048 | Nitric-oxide Synthase, Brain, Rat | 124 |
| NOS2_MOUSE | P29477 | CHEMBL3464 | Nitric Oxide Synthase, Inducible, Mouse | 65 |
| NOS3_BOVIN | P29473 | CHEMBL4802 | Nitric-oxide Synthase, Endothelial, Bovin | 13 |
| NOS3_PIG | Q28969 | CHEMBL3809 | Nitric-oxide Synthase, Endothelial, Pig | 8 |
| NOS3_RAT | Q62600 | CHEMBL1075230 | Nitric Oxide Synthase, Endothelial, Rat | 5 |
| KCNH2_HUMAN | Q12809 | CHEMBL240 | HERG, Human | 2 |
| NOS1_MOUSE | Q9Z0J4 | CHEMBL4719 | Nitric-oxide Synthase, Brain, Mouse | 2 |
| 5HT1A_HUMAN | P08908 | CHEMBL214 | Serotonin 1a (5-HT1a) Receptor, Human | 1 |
| 5HT2A_HUMAN | P28223 | CHEMBL224 | Serotonin 2a (5-HT2a) Receptor, Human | 1 |
| ABP1_HUMAN | P19801 | CHEMBL2118 | Diamine Oxidase, Human | 1 |
| ACM2_HUMAN | P08172 | CHEMBL211 | Muscarinic Acetylcholine Receptor M2, Human | 1 |
| ACM4_HUMAN | P08173 | CHEMBL1821 | Muscarinic Acetylcholine Receptor M4, Human | 1 |
| DDAH1_HUMAN | O94760 | CHEMBL6036 | N(G),N(G)-dimethylarginine Dimethylaminohydrolase 1, Human | 1 |
| DRD2_HUMAN | P14416 | CHEMBL217 | Dopamine D2 Receptor, Human | 1 |
| NOS2_RAT | Q06518 | CHEMBL3051 | Nitric Oxide Synthase, Inducible, Rat | 1 |
| NOS3_MOUSE | P70313 | CHEMBL2643 | Nitric-oxide Synthase, Endothelial, Mouse | 1 |
| P4K2A_HUMAN | Q9BTU6 | CHEMBL2251 | PI4-kinase Type II, Human | 1 |
| P4K2B_HUMAN | Q8TCG2 | CHEMBL3220 | PI4-kinase Type II Beta, Human | 1 |
| PI4KA_HUMAN | P42356 | CHEMBL3667 | PI4-kinase Alpha Subunit, Human | 1 |
| PI4KB_HUMAN | Q9UBF8 | CHEMBL3268 | PI4-kinase Beta Subunit, Human | 1 |
