UCSF

Nitric Oxide Synthase, Inducible, Mouse (194 Compounds)

Swissprot:
NOS2_MOUSE
Stitch:
NOS2_MOUSE
UniProt:
P29477
ChEMBL:
CHEMBL3464
Reactome:
REACT_245499
REACT_198345
PDB:
1DD7 (DOCK)
1DF1 (DOCK)
1DWV (DOCK)
1DWW (DOCK)
1DWX (DOCK)
1JWJ (DOCK)
1JWK (DOCK)
1M8D (DOCK)
1M8E (DOCK)
1M8H (DOCK)
1M8I (DOCK)
1M9T (DOCK)
1N2N (DOCK)
1NOC (DOCK)
1NOD (DOCK)
1NOS (DOCK)
1QOM (DOCK)
1QW4 (DOCK)
1QW5 (DOCK)
1R35 (DOCK)
1VAF (DOCK)
2BHJ (DOCK)
2NOD (DOCK)
2NOS (DOCK)
2ORO (DOCK)
2ORP (DOCK)
2ORQ (DOCK)
2ORR (DOCK)
2ORS (DOCK)
2ORT (DOCK)
2Y37 (DOCK)
3DWJ (DOCK)
3E65 (DOCK)
3E67 (DOCK)
3E68 (DOCK)
3E6L (DOCK)
3E6N (DOCK)
3E6O (DOCK)
3E6T (DOCK)
3E7I (DOCK)
3E7M (DOCK)
3E7T (DOCK)
3EAI (DOCK)
3EBD (DOCK)
3EBF (DOCK)
3GOF (DOCK)
3NOD (DOCK)
3NQS (DOCK)
3NW2 (DOCK)
Nos2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 194 27 8 13
Binding ≤ 1μM 85 12 1 7
Functional ≤ 10μM 9 4 1 1

Reactome Network (2)

Reactome ID Description Species
REACT_245499 Nitric oxide stimulates guanylate cyclase Mus musculus
REACT_198345 Phagosomal maturation (early endosomal stage) Mus musculus
Uniprot Swissprot Chembl Description Number Shared
NOS1_MOUSE Q9Z0J4 CHEMBL4719 Nitric-oxide Synthase, Brain, Mouse 27
NOS3_MOUSE P70313 CHEMBL2643 Nitric-oxide Synthase, Endothelial, Mouse 4

Phagosomal maturation (early endosomal stage)

Uniprot Swissprot Chembl Description Number Shared
NOS1_MOUSE Q9Z0J4 CHEMBL4719 Nitric-oxide Synthase, Brain, Mouse 27
NOS3_MOUSE P70313 CHEMBL2643 Nitric-oxide Synthase, Endothelial, Mouse 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NOS2_HUMAN P35228 CHEMBL4481 Nitric Oxide Synthase, Inducible, Human 702 81 18 26
NOS2_RAT Q06518 CHEMBL3051 Nitric Oxide Synthase, Inducible, Rat 2 2 2 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NOS1_MOUSE Q9Z0J4 CHEMBL4719 Nitric-oxide Synthase, Brain, Mouse 27 4 2 2
NOS3_MOUSE P70313 CHEMBL2643 Nitric-oxide Synthase, Endothelial, Mouse 4 1 1 1

Clustered By Gene (0)

Clustered By Organism (8)

Code Description Substances Purchasable Natural In Man
NOS2-1-E Nitric Oxide Synthase, Inducible (cluster #1 Of 9), Eukaryotic 152 9 1 0
NOS2-2-E Nitric Oxide Synthase, Inducible (cluster #2 Of 9), Eukaryotic 36 6 0 2
NOS2-3-E Nitric Oxide Synthase, Inducible (cluster #3 Of 9), Eukaryotic 71 7 1 2
NOS2-4-E Nitric Oxide Synthase, Inducible (cluster #4 Of 9), Eukaryotic 450 31 2 16
NOS2-5-E Nitric Oxide Synthase, Inducible (cluster #5 Of 9), Eukaryotic 43 5 2 1
NOS2-6-E Nitric Oxide Synthase, Inducible (cluster #6 Of 9), Eukaryotic 2 2 0 1
NOS2-7-E Nitric Oxide Synthase, Inducible (cluster #7 Of 9), Eukaryotic 54 18 11 11
NOS2-8-E Nitric Oxide Synthase, Inducible (cluster #8 Of 9), Eukaryotic 14 11 5 1
NOS2-9-E Nitric Oxide Synthase, Inducible (cluster #9 Of 9), Eukaryotic 34 7 1 0
Uniprot Swissprot Chembl Description Number Shared
NOS1_HUMAN P29475 CHEMBL3568 Nitric-oxide Synthase, Brain, Human 65
NOS1_RAT P29476 CHEMBL3048 Nitric-oxide Synthase, Brain, Rat 64
NOS2_HUMAN P35228 CHEMBL4481 Nitric Oxide Synthase, Inducible, Human 57
NOS3_BOVIN P29473 CHEMBL4802 Nitric-oxide Synthase, Endothelial, Bovin 32
NOS3_HUMAN P29474 CHEMBL4803 Nitric-oxide Synthase, Endothelial, Human 28
NOS1_MOUSE Q9Z0J4 CHEMBL4719 Nitric-oxide Synthase, Brain, Mouse 27
NOS3_MOUSE P70313 CHEMBL2643 Nitric-oxide Synthase, Endothelial, Mouse 4
NOS2_RAT Q06518 CHEMBL3051 Nitric Oxide Synthase, Inducible, Rat 2
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2, Mouse 2
ABP1_HUMAN P19801 CHEMBL2118 Diamine Oxidase, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 1
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 1

Most Common Rings