UCSF
Image of 1H-pyrazolo[3,4-d]pyrimidine

Identity 99% 90% 80% 70% Substructure

1H-pyrazolo[3,4-d]pyrimidine

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
2 1 9 5 4 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 1 3,977 90 109 1 2012-03-07

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 37 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PI4KB_HUMAN Q9UBF8 CHEMBL3268 PI4-kinase Beta Subunit, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RIPK2_HUMAN O43353 CHEMBL5014 Serine/threonine-protein Kinase RIPK2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RIPK2_HUMAN O43353 CHEMBL5014 Serine/threonine-protein Kinase RIPK2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q9BJF5_TOXGO Q9BJF5 CHEMBL1781862 Calmodulin-domain Protein Kinase 1, Toxgo 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase