UCSF

Adenosine A2a Receptor, Guinea Pig (18 Compounds)

Swissprot:
AA2AR_CAVPO
Stitch:
AA2AR_CAVPO
UniProt:
P46616
ChEMBL:
CHEMBL2605
PDB:
ADORA2A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 18 9 3 3
Binding ≤ 1μM 11 7 1 2
Functional ≤ 10μM 39 20 4 2

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 2,605 153 29 23
AA2AR_MOUSE Q60613 CHEMBL2115 Adenosine A2a Receptor, Mouse 5 2 0 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 2,846 130 40 27

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
AA2AR-1-E Adenosine A2a Receptor (cluster #1 Of 4), Eukaryotic 4,969 188 36 30
AA2AR-2-E Adenosine A2a Receptor (cluster #2 Of 4), Eukaryotic 59 29 5 4
AA2AR-3-E Adenosine A2a Receptor (cluster #3 Of 4), Eukaryotic 121 25 12 4
AA2AR-4-E Adenosine A2a Receptor (cluster #4 Of 4), Eukaryotic 33 7 3 3
Uniprot Swissprot Chembl Description Number Shared
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 18
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 16
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 16
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 15
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 15
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 12
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 11
AA3R_RAT P28647 CHEMBL3360 Adenosine A3 Receptor, Rat 11
AA1R_BOVIN P28190 CHEMBL4975 Adenosine A1 Receptor, Bovin 10
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 7
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 4
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 3
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 3
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 3
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 3
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 3
AA1R_CHICK P49892 CHEMBL2114 Adenosine A1 Receptor, Chick 2
AA1R_MOUSE Q60612 CHEMBL3688 Adenosine A1 Receptor, Mouse 2
OXGR1_RAT Q6Y1R5 CHEMBL2325 G Protein-coupled Receptor 80, Rat 2
Z50512 Z50512 CHEMBL369 Cavia Porcellus 2
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY3_HUMAN O60266 CHEMBL3164 Adenylate Cyclase Type III, Human 1
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 1
ADCY6_HUMAN O43306 CHEMBL3221 Adenylate Cyclase Type VI, Human 1
ADCY7_HUMAN P51828 CHEMBL4922 Adenylate Cyclase Type VII, Human 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
ADCY9_HUMAN O60503 CHEMBL2655 Adenylate Cyclase Type IX, Human 1
PDE1A_BOVIN P14100 CHEMBL3774 Phosphodiesterase 1A, Bovin 1
PDE1A_HUMAN P54750 CHEMBL3421 Phosphodiesterase 1A, Human 1
PDE1B_BOVIN Q01061 CHEMBL2650 Phosphodiesterase 1B, Bovin 1
PDE1B_HUMAN Q01064 CHEMBL4425 Phosphodiesterase 1B, Human 1
PDE1B_RAT Q01066 CHEMBL3665 Phosphodiesterase 1B, Rat 1
PDE1C_HUMAN Q14123 CHEMBL4619 Phosphodiesterase 1C, Human 1
PDE1C_RAT Q63421 CHEMBL2651 Phosphodiesterase 1C, Rat 1
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 1
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 1
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 1
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 1
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 1
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 1
PDE5A_HUMAN O76074 CHEMBL1827 Phosphodiesterase 5A, Human 1
PDE7A_HUMAN Q13946 CHEMBL3012 Phosphodiesterase 7A, Human 1
PDE7B_HUMAN Q9NP56 CHEMBL4716 Phosphodiesterase 7B, Human 1
Q9EPR9_RAT Q9EPR9 CHEMBL2740 Phosphodiesterase 1A, Rat 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z50588 Z50588 CHEMBL373 Canis Familiaris 1
Z50591 Z50591 CHEMBL613489 Bos Taurus 1
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 1
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 1
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 1