AA2BR_HUMAN - Adenosine A2b Receptor, Human | ZINC Is Not Commercial - A database of commercially-available compounds

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	1,141	51	14	12
Binding ≤ 1μM	951	31	6	4
Functional ≤ 10μM	412	34	8	4

Reactome ID	Description	Species
REACT_18288	Adenosine P1 receptors	Homo sapiens
REACT_19327	G alpha (s) signalling events	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
AA1R_HUMAN	P30542	CHEMBL226	Adenosine A1 Receptor, Human	842
AA2AR_HUMAN	P29274	CHEMBL251	Adenosine A2a Receptor, Human	975
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	595

G alpha (s) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
AA2AR_HUMAN	P29274	CHEMBL251	Adenosine A2a Receptor, Human	975
ADCY1_HUMAN	Q08828	CHEMBL2899	Brain Adenylate Cyclase 1, Human	1
ADCY2_HUMAN	Q08462	CHEMBL3760	Adenylate Cyclase Type II, Human	1
ADCY3_HUMAN	O60266	CHEMBL3164	Adenylate Cyclase Type III, Human	1
ADCY5_HUMAN	O95622	CHEMBL3189	Adenylate Cyclase Type V, Human	1
ADCY6_HUMAN	O43306	CHEMBL3221	Adenylate Cyclase Type VI, Human	1
ADCY7_HUMAN	P51828	CHEMBL4922	Adenylate Cyclase Type VII, Human	1
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	1
ADCY9_HUMAN	O60503	CHEMBL2655	Adenylate Cyclase Type IX, Human	1
PDE3A_HUMAN	Q14432	CHEMBL241	Phosphodiesterase 3A, Human	1
PDE3B_HUMAN	Q13370	CHEMBL290	Phosphodiesterase 3B, Human	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
AA2BR_MOUSE	Q60614	CHEMBL2237	Adenosine A2b Receptor, Mouse	2	1	0	0
AA2BR_RAT	P29276	CHEMBL2592	Adenosine A2b Receptor, Rat	1,327	64	16	11

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
AA2AR_HUMAN	P29274	CHEMBL251	Adenosine A2a Receptor, Human	856
AA1R_HUMAN	P30542	CHEMBL226	Adenosine A1 Receptor, Human	692
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	502
AA1R_RAT	P25099	CHEMBL318	Adenosine A1 Receptor, Rat	345
AA2AR_RAT	P30543	CHEMBL302	Adenosine A2a Receptor, Rat	282
AA2BR_RAT	P29276	CHEMBL2592	Adenosine A2b Receptor, Rat	147
AA1R_BOVIN	P28190	CHEMBL4975	Adenosine A1 Receptor, Bovin	38
AA3R_RAT	P28647	CHEMBL3360	Adenosine A3 Receptor, Rat	25
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	24
AA1R_RABIT	P34970	CHEMBL3947	Adenosine A1 Receptor, Rabit	15
AA2AR_CAVPO	P46616	CHEMBL2605	Adenosine A2a Receptor, Guinea Pig	15
AA3R_RABIT	O02667	CHEMBL2603	Adenosine A3 Receptor, Rabit	15
Z50592	Z50592	CHEMBL374	Oryctolagus Cuniculus	14
ADCY2_RAT	P26769	CHEMBL2958	Adenylate Cyclase Type II, Rat	8
OXGR1_RAT	Q6Y1R5	CHEMBL2325	G Protein-coupled Receptor 80, Rat	7
ADCY3_RAT	P21932	CHEMBL4864	Adenylate Cyclase Type III, Rat	5
ADCY4_RAT	P26770	CHEMBL2879	Adenylate Cyclase Type IV, Rat	5
ADCY5_RAT	Q04400	CHEMBL2880	Adenylate Cyclase Type V, Rat	5
ADCY6_RAT	Q03343	CHEMBL2975	Adenylate Cyclase Type VI, Rat	5
ADCY8_RAT	P40146	CHEMBL3082	Adenylate Cyclase Type VIII, Rat	5
Z100273	Z100273	CHEMBL612413	P3 Purinoceptor	5
Z50512	Z50512	CHEMBL369	Cavia Porcellus	5
AA2BR_MOUSE	Q60614	CHEMBL2237	Adenosine A2b Receptor, Mouse	4
SAHH_HUMAN	P23526	CHEMBL2664	Adenosylhomocysteinase, Human	4
Z50588	Z50588	CHEMBL373	Canis Familiaris	3
AA1R_MOUSE	Q60612	CHEMBL3688	Adenosine A1 Receptor, Mouse	2
Q72874_9HIV1	Q72874	CHEMBL243	Human Immunodeficiency Virus Type 1 Protease, 9hiv1	2
Z100081	Z100081	CHEMBL613107	PBMC (Peripheral Blood Mononuclear Cells)	2
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	2
Z50587	Z50587	CHEMBL372	Homo Sapiens	2
AA1R_CHICK	P49892	CHEMBL2114	Adenosine A1 Receptor, Chick	1
AA2AR_MOUSE	Q60613	CHEMBL2115	Adenosine A2a Receptor, Mouse	1
AA3R_BOVIN	Q0VC81	CHEMBL1287626	Adenosine Receptor A3, Bovin	1
AA3R_MOUSE	Q61618	CHEMBL1075269	Adenosine Receptor A3, Mouse	1
ADCY1_HUMAN	Q08828	CHEMBL2899	Brain Adenylate Cyclase 1, Human	1
ADCY2_HUMAN	Q08462	CHEMBL3760	Adenylate Cyclase Type II, Human	1
ADCY3_HUMAN	O60266	CHEMBL3164	Adenylate Cyclase Type III, Human	1
ADCY5_HUMAN	O95622	CHEMBL3189	Adenylate Cyclase Type V, Human	1
ADCY6_HUMAN	O43306	CHEMBL3221	Adenylate Cyclase Type VI, Human	1
ADCY7_HUMAN	P51828	CHEMBL4922	Adenylate Cyclase Type VII, Human	1
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	1
ADCY9_HUMAN	O60503	CHEMBL2655	Adenylate Cyclase Type IX, Human	1
CNCG_HUMAN	Q13956	CHEMBL2341	Phosphodiesterase 6H, Human	1
CNRG_HUMAN	P18545	CHEMBL2415	Phosphodiesterase 6G, Human	1
PDE5A_HUMAN	O76074	CHEMBL1827	Phosphodiesterase 5A, Human	1
PDE6A_HUMAN	P16499	CHEMBL3878	Phosphodiesterase 6A, Human	1
PDE6B_HUMAN	P35913	CHEMBL3659	Phosphodiesterase 6B, Human	1
PDE6C_HUMAN	P51160	CHEMBL3977	Phosphodiesterase 6C, Human	1
PDE6D_HUMAN	O43924	CHEMBL3860	Phosphodiesterase 6D, Human	1
Q4VQ11_PIG	Q4VQ11	CHEMBL1075029	A1 Adenosine Receptor, Pig	1
S29A1_HUMAN	Q99808	CHEMBL1997	Equilibrative Nucleoside Transporter 1, Human	1