UCSF

Adenylate Cyclase Type III, Rat (36 Compounds)

Swissprot:
ADCY3_RAT
Stitch:
ADCY3_RAT
UniProt:
P21932
ChEMBL:
CHEMBL4864
PDB:
Adcy3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 36 24 5 5
Binding ≤ 1μM 31 19 4 4
Functional ≤ 10μM 12 3 1 2

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ADCY3_HUMAN O60266 CHEMBL3164 Adenylate Cyclase Type III, Human 24 1 1 0
ADCY3_MOUSE Q8VHH7 CHEMBL2920 Adenylate Cyclase Type III, Mouse 2 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 47 24 5 5
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 36 24 5 5
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 62 29 5 6
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 36 24 5 5
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 36 24 5 5

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
ADCY3-1-E Adenylate Cyclase Type III (cluster #1 Of 2), Eukaryotic 12 11 3 2
ADCY3-2-E Adenylate Cyclase Type III (cluster #2 Of 2), Eukaryotic 51 15 3 3
Uniprot Swissprot Chembl Description Number Shared
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 44
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 40
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 40
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 40
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 40
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 26
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 20
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 20
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 10
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 9
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 9
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 9
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 9
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 9
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 8
AA1R_BOVIN P28190 CHEMBL4975 Adenosine A1 Receptor, Bovin 6
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 6
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 6
AA3R_RAT P28647 CHEMBL3360 Adenosine A3 Receptor, Rat 6
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 5
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 5
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 4
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 4
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 4
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 4
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 3
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 3
AA1R_CHICK P49892 CHEMBL2114 Adenosine A1 Receptor, Chick 3
AA2AR_CAVPO P46616 CHEMBL2605 Adenosine A2a Receptor, Guinea Pig 3
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 3
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 3
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 3
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 3
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 3
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 2
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 2
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 2
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 2
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 2
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 2
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 2
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 2
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 2
PDR5_YEAST P33302 CHEMBL1697658 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 2
Z50594 Z50594 CHEMBL375 Mus Musculus 2
Z80094 Z80094 CHEMBL614558 CHO-MG (Ovarian Cells) 2
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 2
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 1
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 1
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 1
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 1
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 1
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 1
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 1
MTR1B_HUMAN P49286 CHEMBL1946 Melatonin Receptor 1B, Human 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
Q4VQ11_PIG Q4VQ11 CHEMBL1075029 A1 Adenosine Receptor, Pig 1
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1
S29A1_HUMAN Q99808 CHEMBL1997 Equilibrative Nucleoside Transporter 1, Human 1
S29A1_RAT O54698 CHEMBL4604 Equilibrative Nucleoside Transporter 1, Rat 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 1
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1
TRPV1_RAT O35433 CHEMBL5102 Vanilloid Receptor, Rat 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1
Z101682 Z101682 CHEMBL613915 BK Polyomavirus 1
Z102380 Z102380 CHEMBL613680 Ileum 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1
Z50636 Z50636 CHEMBL613725 Sindbis Virus 1

Most Common Rings