UCSF

Melatonin Receptor 1B, Human (866 Compounds)

Swissprot:
MTR1B_HUMAN
Stitch:
MTR1B_HUMAN
UniProt:
P49286
ChEMBL:
CHEMBL1946
Reactome:
REACT_14828
REACT_19231
PDB:
MTNR1B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 866 40 7 5
Binding ≤ 1μM 822 33 5 4
Functional ≤ 10μM 52 17 1 2

Reactome Network (2)

Reactome ID Description Species
REACT_14828 Class A/1 (Rhodopsin-like receptors) Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 800

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 800
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MTR1B_CHICK P51050 CHEMBL4466 Melatonin Receptor 1B, Chick 387 65 7 4

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
MTR1B-1-E Melatonin Receptor 1B (cluster #1 Of 2), Eukaryotic 1,038 61 9 4
MTR1B-2-E Melatonin Receptor 1B (cluster #2 Of 2), Eukaryotic 160 39 3 2
Uniprot Swissprot Chembl Description Number Shared
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 800
MTR1B_CHICK P51050 CHEMBL4466 Melatonin Receptor 1B, Chick 85
MTR1A_CHICK P49285 CHEMBL4555 Melatonin Receptor 1A, Chick 84
MTR1C_CHICK P49288 CHEMBL3196 Melatonin Receptor 1C, Chick 84
NQO2_HUMAN P16083 CHEMBL3959 Quinone Reductase 2, Human 70
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 10
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 9
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
MC3R_HUMAN P41968 CHEMBL4644 Melanocortin Receptor 3, Human 1
MC4R_MOUSE P56450 CHEMBL3719 Melanocortin Receptor 4, Mouse 1
MC4R_RAT P70596 CHEMBL2700 Melanocortin Receptor 4, Rat 1
MC5R_HUMAN P33032 CHEMBL4608 Melanocortin Receptor 5, Human 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1
Z81346 Z81346 CHEMBL614313 Melanophores (Melanophore Cells) 1

Most Common Rings