UCSF

Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast (18 Compounds)

Swissprot:
PDR5_YEAST
Stitch:
PDR5_YEAST
UniProt:
P33302
ChEMBL:
CHEMBL1697658
PDB:
PDR5

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 18 15 12 12
Binding ≤ 1μM 1 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 6
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 6
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 6
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 6
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 5
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 4
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 4
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 4
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 4
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 4
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 4
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 4
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 3
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 3
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 3
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 3
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 3
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 3
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 3
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 3
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 3
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 2
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 2
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 2
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 2
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 2
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 2
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 2
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 2
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 2
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 2
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 2
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 2
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 2
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 2
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 2
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 2
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 2
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
A3EZI9_9HEPC A3EZI9 CHEMBL4893 Hepatitis C Virus NS3 Protease/helicase, 9hepc 1
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 1
BGLR_RAT P06760 CHEMBL4814 Beta-glucuronidase, Rat 1
CHLE_HORSE P81908 CHEMBL5763 Cholinesterase, Horse 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
LYSC1_RAT P00697 CHEMBL2297 Lysozyme C, Rat 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
TRPV1_RAT O35433 CHEMBL5102 Vanilloid Receptor, Rat 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings