UCSF

Dopamine D1 Receptor, Mouse (19 Compounds)

Swissprot:
DRD1_MOUSE
Stitch:
DRD1_MOUSE
UniProt:
Q61616
ChEMBL:
CHEMBL3071
Reactome:
REACT_253535
REACT_242871

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 19 4 2 4
Binding ≤ 1μM 11 3 2 3

Reactome Network (2)

Reactome ID Description Species
REACT_253535 Dopamine receptors Mus musculus
REACT_242871 G alpha (s) signalling events Mus musculus
Uniprot Swissprot Chembl Description Number Shared
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 223 30 11 15
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 653 67 30 30
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 169 16 5 5
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1,231 142 69 68
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 137 8 4 4
DRD4_MOUSE P51436 CHEMBL2574 Dopamine D4 Receptor, Mouse 18 1 0 0

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
DRD1-1-E Dopamine D1 Receptor (cluster #1 Of 4), Eukaryotic 1,944 200 85 86
DRD1-2-E Dopamine D1 Receptor (cluster #2 Of 4), Eukaryotic 281 18 5 8
DRD1-3-E Dopamine D1 Receptor (cluster #3 Of 4), Eukaryotic 1 1 1 1
DRD1-4-E Dopamine D1 Receptor (cluster #4 Of 4), Eukaryotic 4 2 1 1
Uniprot Swissprot Chembl Description Number Shared
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 12
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 11
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 11
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 10
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 9
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 8
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 8
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 8
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 7
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 7
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 7
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 7
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 7
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 7
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 7
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 6
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 5
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 5
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 3
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 3
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 3
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 2
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 2
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 2
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 2
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 2
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 2
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 2
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 2
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 2
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 1
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 1
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 1
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1