UCSF

Phosphodiesterase 7B, Human (19 Compounds)

Swissprot:
PDE7B_HUMAN
Stitch:
PDE7B_HUMAN
UniProt:
Q9NP56
ChEMBL:
CHEMBL4716
Reactome:
REACT_19327
PDB:
1LXW (DOCK)
PDE7B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 19 2 2 2
Binding ≤ 1μM 5 1 1 1

Reactome Network (1)

Reactome ID Description Species
REACT_19327 G alpha (s) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PDE10_HUMAN Q9Y233 CHEMBL4409 Phosphodiesterase 10A, Human 4
PDE11_HUMAN Q9HCR9 CHEMBL2717 Phosphodiesterase 11A, Human 2
PDE1A_HUMAN P54750 CHEMBL3421 Phosphodiesterase 1A, Human 3
PDE1B_HUMAN Q01064 CHEMBL4425 Phosphodiesterase 1B, Human 5
PDE2A_HUMAN O00408 CHEMBL2652 Phosphodiesterase 2A, Human 4
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 6
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 3
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 6
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 5
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 5
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 7
PDE7A_HUMAN Q13946 CHEMBL3012 Phosphodiesterase 7A, Human 16
PDE8A_HUMAN O60658 CHEMBL4640 Phosphodiesterase 8A, Human 1
PDE8B_HUMAN O95263 CHEMBL4408 Phosphodiesterase 8B, Human 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
PDE7A_HUMAN Q13946 CHEMBL3012 Phosphodiesterase 7A, Human 16
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 7
PDE5A_HUMAN O76074 CHEMBL1827 Phosphodiesterase 5A, Human 7
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 6
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 6
PDE7A_RAT O08593 CHEMBL3450 Phosphodiesterase 7A, Rat 6
PDE1B_HUMAN Q01064 CHEMBL4425 Phosphodiesterase 1B, Human 5
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 5
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 5
O77823_PIG O77823 CHEMBL3333 Phosphodiesterase 4A, Pig 4
PDE10_HUMAN Q9Y233 CHEMBL4409 Phosphodiesterase 10A, Human 4
PDE2A_HUMAN O00408 CHEMBL2652 Phosphodiesterase 2A, Human 4
Q864F1_PIG Q864F1 CHEMBL3634 Phosphodiesterase 5, Pig 4
PDE1A_BOVIN P14100 CHEMBL3774 Phosphodiesterase 1A, Bovin 3
PDE1A_HUMAN P54750 CHEMBL3421 Phosphodiesterase 1A, Human 3
PDE1C_HUMAN Q14123 CHEMBL4619 Phosphodiesterase 1C, Human 3
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 3
E1BN64_BOVIN E1BN64 CHEMBL5129 Phosphodiesterase 3B, Bovin 2
PDE11_HUMAN Q9HCR9 CHEMBL2717 Phosphodiesterase 11A, Human 2
AA1R_BOVIN P28190 CHEMBL4975 Adenosine A1 Receptor, Bovin 1
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_CAVPO P46616 CHEMBL2605 Adenosine A2a Receptor, Guinea Pig 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 1
AA3R_RAT P28647 CHEMBL3360 Adenosine A3 Receptor, Rat 1
CNCG_HUMAN Q13956 CHEMBL2341 Phosphodiesterase 6H, Human 1
CNRG_HUMAN P18545 CHEMBL2415 Phosphodiesterase 6G, Human 1
PDE1B_BOVIN Q01061 CHEMBL2650 Phosphodiesterase 1B, Bovin 1
PDE6A_HUMAN P16499 CHEMBL3878 Phosphodiesterase 6A, Human 1
PDE6B_HUMAN P35913 CHEMBL3659 Phosphodiesterase 6B, Human 1
PDE6C_HUMAN P51160 CHEMBL3977 Phosphodiesterase 6C, Human 1
PDE6D_HUMAN O43924 CHEMBL3860 Phosphodiesterase 6D, Human 1
PDE8A_HUMAN O60658 CHEMBL4640 Phosphodiesterase 8A, Human 1
PDE8B_HUMAN O95263 CHEMBL4408 Phosphodiesterase 8B, Human 1
Q8VIE4_RAT Q8VIE4 CHEMBL3386 Phosphodiesterase 7B, Rat 1
S29A1_HUMAN Q99808 CHEMBL1997 Equilibrative Nucleoside Transporter 1, Human 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings