ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (326)
Reactome (0)
Related By:
Pathway (0)
Organism (-1)
Gene (-1)
Org. Clust. (3)
ChEMBL (122)
Rings (17)

Neuronal Acetylcholine Receptor; Alpha4/beta2 (326 Compounds)

Swissprot:: Z104283
Stitch:: Z104283
UniProt:: Z104283
ChEMBL:: CHEMBL1907589

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	326	45	22	13
Binding ≤ 1μM	273	35	14	10
Functional ≤ 10μM	182	9	5	3

Clustered By Gene (0)

Clustered By Organism (3)

Code	Description	Substances	Purchasable	Natural	In Man
Z104283-1-O	Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #1 Of 4), Other	170	33	18	11
Z104283-2-O	Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #2 Of 4), Other	119	15	4	3
Z104283-3-O	Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #3 Of 4), Other	41	1	0	0
Z104283-4-O	Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #4 Of 4), Other	1	1	1	1

Uniprot	Swissprot	Chembl	Description	Number Shared
Z104288	Z104288	CHEMBL1907594	Neuronal Acetylcholine Receptor; Alpha3/beta4	144
Z104290	Z104290	CHEMBL1907596	Neuronal Acetylcholine Receptor; Alpha4/beta2	88
ACHA7_HUMAN	P36544	CHEMBL2492	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human	54
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat	43
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	42
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	40
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	34
ACHB4_HUMAN	P30926	CHEMBL3002	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human	31
ACHD_TORCA	P02718	CHEMBL3916	Acetylcholine Receptor Protein Delta Chain, Torca	29
Z104282	Z104282	CHEMBL1907588	Acetylcholine Receptor; Alpha1/beta1/delta/gamma	29
Z104287	Z104287	CHEMBL1907593	Neuronal Acetylcholine Receptor; Alpha3/beta4	29
Z104281	Z104281	CHEMBL1907587	Neuronal Acetylcholine Receptor; Alpha3/beta2	28
Z104286	Z104286	CHEMBL1907592	Neuronal Acetylcholine Receptor; Alpha2/beta2	25
Z104289	Z104289	CHEMBL1907595	Neuronal Acetylcholine Receptor; Alpha4/beta4	25
ACHA4_RAT	P09483	CHEMBL307	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat	22
ACHB3_HUMAN	Q05901	CHEMBL2586	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human	22
Z104284	Z104284	CHEMBL1907590	Neuronal Acetylcholine Receptor; Alpha2/beta4	20
ACHB4_RAT	P12392	CHEMBL2658	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat	19
ACHB2_RAT	P12390	CHEMBL3001	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat	18
ACHA3_RAT	P04757	CHEMBL3818	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat	17
ACH10_RAT	Q9JLB5	CHEMBL3461	Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat	16
ACHA9_RAT	P43144	CHEMBL2585	Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat	16
ACHA_TORCA	P02710	CHEMBL3097	Acetylcholine Receptor Protein Alpha Chain, Torca	16
ACHA2_RAT	P12389	CHEMBL2584	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat	15
ACHA5_RAT	P20420	CHEMBL4960	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat	14
ACHA6_RAT	P43143	CHEMBL4747	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat	14
ACHA_RAT	P25108	CHEMBL3599	Acetylcholine Receptor Protein Alpha Chain, Rat	14
ACHB3_RAT	P12391	CHEMBL4568	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat	14
ACHB_RAT	P25109	CHEMBL2666	Acetylcholine Receptor Protein Beta Chain, Rat	14
ACHB_TORCA	P02712	CHEMBL3803	Acetylcholine Receptor Protein Beta Chain, Torca	14
ACHG_TORCA	P02714	CHEMBL4019	Acetylcholine Receptor Protein Gamma Chain, Torca	14
ACHD_HUMAN	Q07001	CHEMBL3011	Acetylcholine Receptor Protein Delta Chain, Human	12
Z104285	Z104285	CHEMBL1907591	Neuronal Acetylcholine Receptor; Alpha4/beta4	11
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human	10
ACHA4_MOUSE	O70174	CHEMBL4457	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Mouse	7
ACHA_HUMAN	P02708	CHEMBL4808	Acetylcholine Receptor Protein Alpha Chain, Human	7
ACHB_HUMAN	P11230	CHEMBL3355	Acetylcholine Receptor Protein Beta Chain, Human	7
Q8BGP7_MOUSE	Q8BGP7	CHEMBL2235	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Mouse	7
ACHA7_MOUSE	P49582	CHEMBL3365	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse	6
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) Receptor, Human	5
ACES_HUMAN	P22303	CHEMBL220	Acetylcholinesterase, Human	5
ACH10_HUMAN	Q9GZZ6	CHEMBL2551	Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Human	4
ACHA5_HUMAN	P30532	CHEMBL2454	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human	4
ACHA6_HUMAN	Q15825	CHEMBL2356	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human	4
ACHE_HUMAN	Q04844	CHEMBL2484	Acetylcholine Receptor Protein Epsilon Chain, Human	4
ACHG_HUMAN	P07510	CHEMBL2613	Acetylcholine Receptor Protein Gamma Chain, Human	4
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	4
Z81074	Z81074	CHEMBL614687	K177cell Line	4
5HT3B_HUMAN	O95264	CHEMBL3895	Serotonin 3b (5-HT3b) Receptor, Human	3
5HT3C_HUMAN	Q8WXA8	CHEMBL4795	Serotonin 3c (5-HT3c) Receptor, Human	3
5HT3D_HUMAN	Q70Z44	CHEMBL4673	Serotonin 3d (5-HT3d) Receptor, Human	3
5HT3E_HUMAN	A5X5Y0	CHEMBL3812	Serotonin 3e (5-HT3e) Receptor, Human	3
CHLE_HUMAN	P06276	CHEMBL1914	Butyrylcholinesterase, Human	3
HRH3_HUMAN	Q9Y5N1	CHEMBL264	Histamine H3 Receptor, Human	3
ITA5_HUMAN	P08648	CHEMBL3955	Fibronectin Receptor Alpha, Human	3
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	3
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	2
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	2
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	2
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	2
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	2
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	2
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	2
AA1R_HUMAN	P30542	CHEMBL226	Adenosine A1 Receptor, Human	2
AA2AR_HUMAN	P29274	CHEMBL251	Adenosine A2a Receptor, Human	2
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	2
ACHA6_MOUSE	Q9R0W9	CHEMBL6183	Neuronal Acetylcholine Receptor Subunit Alpha-6, Mouse	2
ACHB3_MOUSE	Q8BMN3	CHEMBL1781863	Neuronal Acetylcholine Receptor Subunit Beta-3, Mouse	2
ACHB4_MOUSE	Q8R493	CHEMBL1255157	Neuronal Acetylcholine Receptor Subunit Beta-4, Mouse	2
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	2
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	2
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	2
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	2
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	2
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	2
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	2
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	2
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	2
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	2
ADRB1_HUMAN	P08588	CHEMBL213	Beta-1 Adrenergic Receptor, Human	2
ADRB2_HUMAN	P07550	CHEMBL210	Beta-2 Adrenergic Receptor, Human	2
AOFA_HUMAN	P21397	CHEMBL1951	Monoamine Oxidase A, Human	2
CNR1_HUMAN	P21554	CHEMBL218	Cannabinoid CB1 Receptor, Human	2
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	2
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	2
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	2
EDNRA_HUMAN	P25101	CHEMBL252	Endothelin Receptor ET-A, Human	2
GASR_HUMAN	P32239	CHEMBL298	Cholecystokinin B Receptor, Human	2
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	2
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	2
HRH2_HUMAN	P25021	CHEMBL1941	Histamine H2 Receptor, Human	2
LYN_HUMAN	P07948	CHEMBL3905	Tyrosine-protein Kinase Lyn, Human	2
MC4R_HUMAN	P32245	CHEMBL259	Melanocortin Receptor 4, Human	2
MK14_HUMAN	Q16539	CHEMBL260	MAP Kinase P38 Alpha, Human	2
MT3_HUMAN	P25713	CHEMBL1250357	Metallothionein-3, Human	2
MTR1A_HUMAN	P48039	CHEMBL1945	Melatonin Receptor 1A, Human	2
NISCH_HUMAN	Q9Y2I1	CHEMBL3923	Nischarin, Human	2
NK1R_HUMAN	P25103	CHEMBL249	Neurokinin 1 Receptor, Human	2
NK2R_HUMAN	P21452	CHEMBL2327	Neurokinin 2 Receptor, Human	2
NPY1R_HUMAN	P25929	CHEMBL4777	Neuropeptide Y Receptor Type 1, Human	2
NTR1_HUMAN	P30989	CHEMBL4123	Neurotensin Receptor 1, Human	2
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	2
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	2
SC5A7_HUMAN	Q9GZV3	CHEMBL4507	High-affinity Choline Transporter, Human	2
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	2
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	2
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	2
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	2
Z80175	Z80175	CHEMBL614585	IMR-32 (Neuroblastoma Cells)	2
Z80545	Z80545	CHEMBL615012	TE-671	2
ACES_MOUSE	P21836	CHEMBL3198	Acetylcholinesterase, Mouse	1
ACHA4_CHICK	P09482	CHEMBL5569	Neuronal Acetylcholine Receptor Subunit Alpha-4, Chick	1
ACHP_LYMST	P58154	CHEMBL6084	Acetylcholine-binding Protein, Lymst	1
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	1
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	1
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	1
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	1
KCNN1_HUMAN	Q92952	CHEMBL2369	Small Conductance Calcium-activated Potassium Channel Protein 1, Human	1
KCNN2_HUMAN	Q9H2S1	CHEMBL4469	Small Conductance Calcium-activated Potassium Channel Protein 2, Human	1
KCNN3_HUMAN	Q9UGI6	CHEMBL3381	Small Conductance Calcium-activated Potassium Channel Protein 3, Human	1
KCNN3_RAT	P70605	CHEMBL3780	Small Conductance Calcium-activated Potassium Channel Protein 3, Rat	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1