| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 557 | 10 | 0 | 1 |
| Binding ≤ 1μM | 414 | 3 | 0 | 0 |
| Functional ≤ 10μM | 325 | 5 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_15344 | Chemokine receptors bind chemokines | Homo sapiens |
| REACT_19231 | G alpha (i) signalling events | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| 5HT1A_HUMAN | P08908 | CHEMBL214 | Serotonin 1a (5-HT1a) Receptor, Human | 1 |
| ACM2_HUMAN | P08172 | CHEMBL211 | Muscarinic Acetylcholine Receptor M2, Human | 8 |
| ADA2A_HUMAN | P08913 | CHEMBL1867 | Alpha-2a Adrenergic Receptor, Human | 1 |
| ADA2C_HUMAN | P18825 | CHEMBL1916 | Alpha-2c Adrenergic Receptor, Human | 1 |
| DRD2_HUMAN | P14416 | CHEMBL217 | Dopamine D2 Receptor, Human | 1 |
| DRD3_HUMAN | P35462 | CHEMBL234 | Dopamine D3 Receptor, Human | 1 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| CXCR3_CANFA | Q5KSK8 | CHEMBL1075194 | C-X-C Chemokine Receptor Type 3, Canine | 1 | 0 | 0 | 0 |
| CXCR3_MOUSE | O88410 | CHEMBL5200 | C-X-C Chemokine Receptor Type 3, Mouse | 17 | 0 | 0 | 0 |
| CXCR3_RAT | Q9JII9 | CHEMBL1075172 | C-X-C Chemokine Receptor Type 3, Rat | 9 | 0 | 0 | 0 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| CXCR1_HUMAN | P25024 | CHEMBL4029 | Interleukin-8 Receptor A, Human | 217 | 2 | 1 | 1 |
| CXCR2_HUMAN | P25025 | CHEMBL2434 | Interleukin-8 Receptor B, Human | 470 | 6 | 0 | 0 |
| CXCR4_HUMAN | P61073 | CHEMBL2107 | C-X-C Chemokine Receptor Type 4, Human | 106 | 4 | 1 | 1 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| CXCR3-1-E | C-X-C Chemokine Receptor Type 3 (cluster #1 Of 2), Eukaryotic | 354 | 7 | 0 | 0 |
| CXCR3-2-E | C-X-C Chemokine Receptor Type 3 (cluster #2 Of 2), Eukaryotic | 206 | 3 | 0 | 1 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| CXCR3_MOUSE | O88410 | CHEMBL5200 | C-X-C Chemokine Receptor Type 3, Mouse | 65 |
| CXCR3_RAT | Q9JII9 | CHEMBL1075172 | C-X-C Chemokine Receptor Type 3, Rat | 16 |
| ACM1_HUMAN | P11229 | CHEMBL216 | Muscarinic Acetylcholine Receptor M1, Human | 10 |
| ACM2_HUMAN | P08172 | CHEMBL211 | Muscarinic Acetylcholine Receptor M2, Human | 8 |
| ACM3_HUMAN | P20309 | CHEMBL245 | Muscarinic Acetylcholine Receptor M3, Human | 6 |
| Z104303 | Z104303 | CHEMBL1907609 | Muscarinic Acetylcholine Receptor | 6 |
| 5HT1A_HUMAN | P08908 | CHEMBL214 | Serotonin 1a (5-HT1a) Receptor, Human | 1 |
| 5HT2A_HUMAN | P28223 | CHEMBL224 | Serotonin 2a (5-HT2a) Receptor, Human | 1 |
| 5HT2B_HUMAN | P41595 | CHEMBL1833 | Serotonin 2b (5-HT2b) Receptor, Human | 1 |
| 5HT6R_HUMAN | P50406 | CHEMBL3371 | Serotonin 6 (5-HT6) Receptor, Human | 1 |
| ADA2A_HUMAN | P08913 | CHEMBL1867 | Alpha-2a Adrenergic Receptor, Human | 1 |
| ADA2C_HUMAN | P18825 | CHEMBL1916 | Alpha-2c Adrenergic Receptor, Human | 1 |
| ADRB1_HUMAN | P08588 | CHEMBL213 | Beta-1 Adrenergic Receptor, Human | 1 |
| B8PY99_MACMU | B8PY99 | CHEMBL1075186 | CXC Chemokine Receptor 3, Macmu | 1 |
| CXCR3_CANFA | Q5KSK8 | CHEMBL1075194 | C-X-C Chemokine Receptor Type 3, Canine | 1 |
| DRD1_HUMAN | P21728 | CHEMBL2056 | Dopamine D1 Receptor, Human | 1 |
| DRD2_HUMAN | P14416 | CHEMBL217 | Dopamine D2 Receptor, Human | 1 |
| DRD3_HUMAN | P35462 | CHEMBL234 | Dopamine D3 Receptor, Human | 1 |