ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (109)
Reactome (2)
Related By:
Pathway (22)
Organism (1)
Gene (0)
Org. Clust. (1)
ChEMBL (89)
Rings (8)

Serotonin 1f (5-HT1f) Receptor, Human (109 Compounds)

Swissprot:: 5HT1F_HUMAN
Stitch:: 5HT1F_HUMAN
UniProt:: P30939
ChEMBL:: CHEMBL1805
Reactome:: REACT_19231; REACT_17064
PDB:: HTR1F

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	109	8	3	3
Binding ≤ 1μM	103	6	3	3
Functional ≤ 10μM	18	2	2	2

Reactome ID	Description	Species
REACT_19231	G alpha (i) signalling events	Homo sapiens
REACT_17064	Serotonin receptors	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	72
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	68
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	73
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	22
5HT5A_HUMAN	P47898	CHEMBL3426	Serotonin 5a (5-HT5a) Receptor, Human	7
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	1
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	2
ADA2C_HUMAN	P18825	CHEMBL1916	Alpha-2c Adrenergic Receptor, Human	2
ADCY1_HUMAN	Q08828	CHEMBL2899	Brain Adenylate Cyclase 1, Human	1
ADCY2_HUMAN	Q08462	CHEMBL3760	Adenylate Cyclase Type II, Human	1
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	1
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	13
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	14
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	6

Serotonin receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	72
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	68
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	73
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	22
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	18
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	17
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	26
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	11
5HT5A_HUMAN	P47898	CHEMBL3426	Serotonin 5a (5-HT5a) Receptor, Human	7
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	21
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	19

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	245	97	43	43

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
5HT1F-1-E	Serotonin 1f (5-HT1f) Receptor (cluster #1 Of 2), Eukaryotic	303	68	36	29
5HT1F-2-E	Serotonin 1f (5-HT1f) Receptor (cluster #2 Of 2), Eukaryotic	54	40	9	18

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	73
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	72
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	68
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	26
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	21
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	20
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	19
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	18
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	17
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	13
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	13
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	13
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	10
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) Receptor, Human	8
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	7
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	7
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	7
5HT3B_HUMAN	O95264	CHEMBL3895	Serotonin 3b (5-HT3b) Receptor, Human	6
5HT3E_HUMAN	A5X5Y0	CHEMBL3812	Serotonin 3e (5-HT3e) Receptor, Human	6
5HT5A_HUMAN	P47898	CHEMBL3426	Serotonin 5a (5-HT5a) Receptor, Human	6
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	6
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	6
5HT3C_HUMAN	Q8WXA8	CHEMBL4795	Serotonin 3c (5-HT3c) Receptor, Human	5
5HT3D_HUMAN	Q70Z44	CHEMBL4673	Serotonin 3d (5-HT3d) Receptor, Human	5
5HT5A_RAT	P35364	CHEMBL4655	Serotonin 5a (5-HT5a) Receptor, Rat	5
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	5
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	5
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	5
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	5
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	4
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	3
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	3
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	3
DRD5_HUMAN	P21918	CHEMBL1850	Dopamine D5 Receptor, Human	3
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	3
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	3
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	3
5HT1A_MOUSE	Q64264	CHEMBL3737	Serotonin 1a (5-HT1a) Receptor, Mouse	2
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	2
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	2
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	2
5HT3A_MOUSE	P23979	CHEMBL4972	Serotonin 3a (5-HT3a) Receptor, Mouse	2
5HT3A_RAT	P35563	CHEMBL2411	Serotonin 3a (5-HT3a) Receptor, Rat	2
5HT3B_RAT	Q9JJ16	CHEMBL3458	Serotonin 3b (5-HT3b) Receptor, Rat	2
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	2
ADA2C_HUMAN	P18825	CHEMBL1916	Alpha-2c Adrenergic Receptor, Human	2
ADRB2_HUMAN	P07550	CHEMBL210	Beta-2 Adrenergic Receptor, Human	2
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	2
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	2
Z50588	Z50588	CHEMBL373	Canis Familiaris	2
Z50592	Z50592	CHEMBL374	Oryctolagus Cuniculus	2
5HT1D_PIG	P79400	CHEMBL4105	Serotonin 1d (5-HT1d) Receptor, Pig	1
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	1
5HT3B_MOUSE	Q9JHJ5	CHEMBL3781	Serotonin 3b (5-HT3b) Receptor, Mouse	1
5HT4R_RAT	Q62758	CHEMBL4317	Serotonin 4 (5-HT4) Receptor, Rat	1
5HT7R_RAT	P32305	CHEMBL3223	Serotonin 7 (5-HT7) Receptor, Rat	1
ACM5_RAT	P08911	CHEMBL277	Muscarinic Acetylcholine Receptor M5, Rat	1
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	1
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	1
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	1
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	1
ADA1D_RAT	P23944	CHEMBL326	Alpha-1d Adrenergic Receptor, Rat	1
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a Adrenergic Receptor, Bovin	1
ADA2B_BOVIN	O77700	CHEMBL3523	Alpha-2b Adrenergic Receptor, Bovin	1
ADCY1_HUMAN	Q08828	CHEMBL2899	Brain Adenylate Cyclase 1, Human	1
ADCY2_HUMAN	Q08462	CHEMBL3760	Adenylate Cyclase Type II, Human	1
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	1
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	1
HRH1_CAVPO	P31389	CHEMBL3943	Histamine H1 Receptor, Guinea Pig	1
HRH1_RAT	P31390	CHEMBL4701	Histamine H1 Receptor, Rat	1
HRH2_CAVPO	P47747	CHEMBL2882	Histamine H2 Receptor, Guinea Pig	1
HRH2_RAT	P25102	CHEMBL4654	Histamine H2 Receptor, Rat	1
HRH3_RAT	Q9QYN8	CHEMBL4124	Histamine H3 Receptor, Rat	1
HRH4_RAT	Q91ZY1	CHEMBL4468	Histamine H4 Receptor, Rat	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
Q63380_RAT	Q63380	CHEMBL6184	Transporter, Rat	1
SC6A3_BOVIN	P27922	CHEMBL2986	Dopamine Transporter, Bovin	1
SC6A3_MACFA	Q9GJT6	CHEMBL5032	Dopamine Transporter, Macfa	1
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	1
SC6A4_MOUSE	Q60857	CHEMBL4642	Serotonin Transporter, Mouse	1
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	1
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	1
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	1
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	1
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	1
UR2R_HUMAN	Q9UKP6	CHEMBL3764	Urotensin II Receptor, Human	1
Z100251	Z100251	CHEMBL612442	Monoclonal Antibody (mAb) 2E2	1
Z50796	Z50796	CHEMBL614874	Monkey	1
Z80334	Z80334	CHEMBL613828	NG108-15 (Neuroblastoma-glioma Hybrid Cells)	1