UCSF

C-C Chemokine Receptor Type 1, Human (383 Compounds)

Swissprot:
CCR1_HUMAN
Stitch:
CCR1_HUMAN
UniProt:
P32246
ChEMBL:
CHEMBL2413
Reactome:
REACT_15344
REACT_19231
PDB:
1Y5D (DOCK)
CCR1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 383 10 0 0
Binding ≤ 1μM 303 7 0 0
Functional ≤ 10μM 190 7 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_15344 Chemokine receptors bind chemokines Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 19
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 31
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 12
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 14
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 19
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 31
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 12
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 14
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 2
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CCR1_MOUSE P51675 CHEMBL3872 C-C Chemokine Receptor Type 1, Mouse 28 4 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 1,214 6 1 2
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 908 15 2 1
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 238 6 1 1
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 1,843 7 2 4
CCR7_HUMAN P32248 CHEMBL4594 C-C Chemokine Receptor Type 7, Human 1 0 0 0
CCR8_HUMAN P51685 CHEMBL4596 C-C Chemokine Receptor Type 8, Human 68 3 0 0
CCR9_HUMAN P51686 CHEMBL5815 C-C Chemokine Receptor Type 9, Human 1 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CCR1_MOUSE P51675 CHEMBL3872 C-C Chemokine Receptor Type 1, Mouse 41
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 31
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 19
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 14
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 12
Q9JLY8_RAT Q9JLY8 CHEMBL5499 C-C Chemokine Receptor Type 1, Rat 8
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 7
CCR3_MOUSE P51678 CHEMBL3406 C-C Chemokine Receptor Type 3, Mouse 4
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 2
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 2
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 2
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 2
CCR3_RAT O54814 CHEMBL3928 C-C Chemokine Receptor Type 3, Rat 2
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 2
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 2
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 2
SC6A3_BOVIN P27922 CHEMBL2986 Dopamine Transporter, Bovin 2
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 2
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 2
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 2
US28_HCMVA P69332 CHEMBL4259 Human Herpesvirus 5 Chemokine Receptor, Hcmva 2
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 1
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 1
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 1
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z80107 Z80107 CHEMBL614564 COS-7 (Kidney Cells) 1

Most Common Rings