UCSF
Image of 1,4-diazepane

Identity 99% 90% 80% 70% Substructure

1,4-diazepane

PubMed — Wikipedia — Google

Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 7 5 2 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 0 35,968 45 4,672 0 2012-03-07

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
OX1R_HUMAN O43613 CHEMBL5113 Orexin Receptor 1, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OX1R_HUMAN O43613 CHEMBL5113 Orexin Receptor 1, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OX1R_HUMAN O43613 CHEMBL5113 Orexin Receptor 1, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OX2R_HUMAN O43614 CHEMBL4792 Orexin Receptor 2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OX2R_HUMAN O43614 CHEMBL4792 Orexin Receptor 2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OXYR_HUMAN P30559 CHEMBL2049 Oxytocin Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
EHMT2_HUMAN Q96KQ7 CHEMBL6032 Histone-lysine N-methyltransferase, H3 Lysine-9 Specific 3, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
EHMT2_HUMAN Q96KQ7 CHEMBL6032 Histone-lysine N-methyltransferase, H3 Lysine-9 Specific 3, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
OX2R_HUMAN O43614 CHEMBL4792 Orexin Receptor 2, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
OXYR_HUMAN P30559 CHEMBL2049 Oxytocin Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
V2R_HUMAN P30518 CHEMBL1790 Vasopressin V2 Receptor, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EHMT1_HUMAN Q9H9B1 CHEMBL6031 Histone-lysine N-methyltransferase, H3 Lysine-9 Specific 5, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EHMT1_HUMAN Q9H9B1 CHEMBL6031 Histone-lysine N-methyltransferase, H3 Lysine-9 Specific 5, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMUR1_HUMAN Q9HB89 CHEMBL1075178 Neuromedin-U Receptor 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMUR2_HUMAN Q9GZQ4 CHEMBL1075144 Neuromedin-U Receptor 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PARP1_HUMAN P09874 CHEMBL3105 Poly [ADP-ribose] Polymerase-1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PARP1_HUMAN P09874 CHEMBL3105 Poly [ADP-ribose] Polymerase-1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
V2R_HUMAN P30518 CHEMBL1790 Vasopressin V2 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase