UCSF
Image of 3-pyrrolin-2-one

Identity 99% 90% 80% 70% Substructure

3-pyrrolin-2-one

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 6 4 1 1 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 26 6,740 133 17 4 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
MDM2_HUMAN Q00987 CHEMBL5023 P53-binding Protein Mdm-2, Human 36 Annotations Catalogs SMILES SDF Mol2 Flexibase
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
MDM2_HUMAN Q00987 CHEMBL5023 P53-binding Protein Mdm-2, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RENI_HUMAN P00797 CHEMBL286 Renin, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RENI_HUMAN P00797 CHEMBL286 Renin, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104305 Z104305 CHEMBL1907611 Tumour Suppressor P53/oncoprotein Mdm2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCND2_HUMAN P30279 CHEMBL3613 G1/S-specific Cyclin D2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCND2_HUMAN P30279 CHEMBL3613 G1/S-specific Cyclin D2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
E2QDN0_ECOLX E2QDN0 CHEMBL1795153 Thymidylate Synthase (EC 2.1.1.45) (TS) (TSase), Ecolx 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
E2QDN0_ECOLX E2QDN0 CHEMBL1795153 Thymidylate Synthase (EC 2.1.1.45) (TS) (TSase), Ecolx 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PKD1_HUMAN P98161 CHEMBL5772 Polycystin-1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PKD1_HUMAN P98161 CHEMBL5772 Polycystin-1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase