UCSF
Image of Morpholine

Identity 99% 90% 80% 70% Substructure

Morpholine

PubMed — Wikipedia — Google

Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 6 4 1 1 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 104 196,091 422 12,120 8 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 73 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 35 Annotations Catalogs SMILES SDF Mol2 Flexibase
DGAT1_HUMAN O75907 CHEMBL6009 Diacylglycerol O-acyltransferase 1, Human 32 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 32 Annotations Catalogs SMILES SDF Mol2 Flexibase
DGAT1_HUMAN O75907 CHEMBL6009 Diacylglycerol O-acyltransferase 1, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_HUMAN P35610 CHEMBL2782 Acyl Coenzyme A:cholesterol Acyltransferase 1, Human 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 28 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_HUMAN P35610 CHEMBL2782 Acyl Coenzyme A:cholesterol Acyltransferase 1, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
DCMC_HUMAN O95822 CHEMBL4698 Malonyl-CoA Decarboxylase, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
DCMC_HUMAN O95822 CHEMBL4698 Malonyl-CoA Decarboxylase, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80240 Z80240 CHEMBL614129 MDA-MB-361 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A9_HUMAN P48067 CHEMBL2337 Glycine Transporter 1, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A9_HUMAN P48067 CHEMBL2337 Glycine Transporter 1, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTLR_HUMAN O43193 CHEMBL2203 Motilin Receptor, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTLR_HUMAN O43193 CHEMBL2203 Motilin Receptor, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNA5_HUMAN P22460 CHEMBL4306 Voltage-gated Potassium Channel Subunit Kv1.5, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A9_MOUSE P28571 CHEMBL1075303 Sodium- And Chloride-dependent Glycine Transporter 1, Mouse 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A9_MOUSE P28571 CHEMBL1075303 Sodium- And Chloride-dependent Glycine Transporter 1, Mouse 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A9_RAT P28572 CHEMBL4556 Glycine Transporter 1, Rat 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A9_RAT P28572 CHEMBL4556 Glycine Transporter 1, Rat 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104288 Z104288 CHEMBL1907594 Neuronal Acetylcholine Receptor; Alpha3/beta4 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_BOVIN P28190 CHEMBL4975 Adenosine A1 Receptor, Bovin 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR1_RAT P35353 CHEMBL4649 Corticotropin Releasing Factor Receptor 1, Rat 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR1_RAT P35353 CHEMBL4649 Corticotropin Releasing Factor Receptor 1, Rat 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPO3_BACSU P13267 CHEMBL3897 DNA Polymerase III, Bacsu 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPO3_BACSU P13267 CHEMBL3897 DNA Polymerase III, Bacsu 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB4_HUMAN Q15303 CHEMBL3009 Receptor Protein-tyrosine Kinase ErbB-4, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ERBB4_HUMAN Q15303 CHEMBL3009 Receptor Protein-tyrosine Kinase ErbB-4, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNA3_HUMAN P22001 CHEMBL4633 Voltage-gated Potassium Channel Subunit Kv1.3, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
V1BR_HUMAN P47901 CHEMBL1921 Vasopressin V1b Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z103205 Z103205 CHEMBL1075390 A431 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80070 Z80070 CHEMBL614543 CEM_SS 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
BKRB1_HUMAN P46663 CHEMBL4308 Bradykinin B1 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR1_HUMAN P34998 CHEMBL1800 Corticotropin Releasing Factor Receptor 1, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR1_HUMAN P34998 CHEMBL1800 Corticotropin Releasing Factor Receptor 1, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
HYES_HUMAN P34913 CHEMBL2409 Epoxide Hydratase, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
INCE_HUMAN Q9NQS7 CHEMBL5177 Inner Centromere Protein, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
INCE_HUMAN Q9NQS7 CHEMBL5177 Inner Centromere Protein, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase