UCSF

Corticotropin Releasing Factor Receptor 1, Human (1,345 Compounds)

Swissprot:
CRFR1_HUMAN
Stitch:
CRFR1_HUMAN
UniProt:
P34998
ChEMBL:
CHEMBL1800
Reactome:
REACT_18372
REACT_19327
PDB:
2L27 (DOCK)
3EHS (DOCK)
3EHT (DOCK)
3EHU (DOCK)
CRHR1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,345 9 3 3
Binding ≤ 1μM 1,162 7 3 3
Functional ≤ 10μM 167 2 1 1

Reactome Network (2)

Reactome ID Description Species
REACT_18372 Class B/2 (Secretin family receptors) Homo sapiens
REACT_19327 G alpha (s) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CRFR2_HUMAN Q13324 CHEMBL4069 Corticotropin Releasing Factor Receptor 2, Human 3

G alpha (s) signalling events

Uniprot Swissprot Chembl Description Number Shared
CRFR2_HUMAN Q13324 CHEMBL4069 Corticotropin Releasing Factor Receptor 2, Human 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CRFR1_MOUSE P35347 CHEMBL2446 Corticotropin Releasing Factor Receptor 1, Mouse 2 0 0 0
CRFR1_RAT P35353 CHEMBL4649 Corticotropin Releasing Factor Receptor 1, Rat 621 4 0 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CRFR2_HUMAN Q13324 CHEMBL4069 Corticotropin Releasing Factor Receptor 2, Human 1 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
CRFR1-1-E Corticotropin Releasing Factor Receptor 1 (cluster #1 Of 3), Eukaryotic 1,972 9 2 2
CRFR1-2-E Corticotropin Releasing Factor Receptor 1 (cluster #2 Of 3), Eukaryotic 1 1 1 1
CRFR1-3-E Corticotropin Releasing Factor Receptor 1 (cluster #3 Of 3), Eukaryotic 0 0 0 0
Uniprot Swissprot Chembl Description Number Shared
CRFR1_RAT P35353 CHEMBL4649 Corticotropin Releasing Factor Receptor 1, Rat 18
CRFR2_HUMAN Q13324 CHEMBL4069 Corticotropin Releasing Factor Receptor 2, Human 3
CRFR2_RAT P47866 CHEMBL3581 Corticotropin Releasing Factor Receptor 2, Rat 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 2
Z81011 Z81011 CHEMBL614840 Human Cell Lines 2
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
GSHR_YEAST P41921 CHEMBL4119 Glutathione Reductase, Yeast 1
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 1
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 1

Most Common Rings