UCSF

Inner Centromere Protein, Human (33 Compounds)

Swissprot:
INCE_HUMAN
Stitch:
INCE_HUMAN
UniProt:
Q9NQS7
ChEMBL:
CHEMBL5177
Reactome:
REACT_682
REACT_150425
REACT_150471
PDB:
2QFA (DOCK)
INCENP

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 33 1 0 0
Binding ≤ 1μM 33 1 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_682 Mitotic Prometaphase Homo sapiens
REACT_150425 Resolution of Sister Chromatid Cohesion Homo sapiens
REACT_150471 Separation of Sister Chromatids Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 33

Resolution of Sister Chromatid Cohesion

Uniprot Swissprot Chembl Description Number Shared
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 33

Separation of Sister Chromatids

Uniprot Swissprot Chembl Description Number Shared
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 33

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 33
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 31
TPX2_HUMAN Q9ULW0 CHEMBL5389 Targeting Protein For Xklp2, Human 7
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 2
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 1
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 1
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 1
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 1
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 1
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 1
SIK1_HUMAN P57059 CHEMBL6082 Serine/threonine-protein Kinase SIK1, Human 1
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 1
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 1
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 1
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 1

Most Common Rings