ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (335)
Reactome (0)
Related By:
Pathway (0)
Organism (1)
Gene (0)
Org. Clust. (1)
ChEMBL (40)
Rings (18)

Mineralocorticoid Receptor, Human (335 Compounds)

Swissprot:: MCR_HUMAN
Stitch:: MCR_HUMAN
UniProt:: P08235
ChEMBL:: CHEMBL1994
PDB:: 1Y9R (DOCK); 1YA3 (DOCK); 2A3I (DOCK); 2AA2 (DOCK); 2AA5 (DOCK); 2AA6 (DOCK); 2AA7 (DOCK); 2AAX (DOCK); 2AB2 (DOCK); 2ABI (DOCK); 2OAX (DOCK); 3VHU (DOCK); 3VHV (DOCK); NR3C2

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	335	12	7	8
Binding ≤ 1μM	254	11	5	6
Functional ≤ 10μM	259	11	7	8

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
MCR_RAT	P22199	CHEMBL3507	Mineralocorticoid Receptor, Rat	29	4	4	3

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
MCR-1-E	Mineralocorticoid Receptor (cluster #1 Of 2), Eukaryotic	19	13	8	9
MCR-2-E	Mineralocorticoid Receptor (cluster #2 Of 2), Eukaryotic	333	1	1	0

Uniprot	Swissprot	Chembl	Description	Number Shared
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	404
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	333
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	209
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	37
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	32
MCR_RAT	P22199	CHEMBL3507	Mineralocorticoid Receptor, Rat	18
GCR_RAT	P06536	CHEMBL3368	Glucocorticoid Receptor, Rat	7
NR1I2_HUMAN	O75469	CHEMBL3401	Pregnane X Receptor, Human	5
Z80110	Z80110	CHEMBL613507	CV-1 (Kidney Cells)	4
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	3
ANDR_MOUSE	P19091	CHEMBL3056	Androgen Receptor, Mouse	2
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	2
GCR_MOUSE	P06537	CHEMBL3144	Glucocorticoid Receptor, Mouse	2
PRGR_CHICK	P07812	CHEMBL3304	Progesterone Receptor, Chick	2
Z80712	Z80712	CHEMBL614361	T47D (Breast Carcinoma Cells)	2
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	1
ESR1_RAT	P06211	CHEMBL2724	Estrogen Receptor Alpha, Rat	1
ESR2_RAT	Q62986	CHEMBL3021	Estrogen Receptor Beta, Rat	1
GLNA_HUMAN	P15104	CHEMBL4612	Glutamine Synthetase, Human	1
GPBAR_HUMAN	Q8TDU6	CHEMBL5409	G-protein Coupled Bile Acid Receptor 1, Human	1
NR1H4_HUMAN	Q96RI1	CHEMBL2047	Bile Acid Receptor FXR, Human	1
NR1H4_MOUSE	Q60641	CHEMBL5343	Bile Acid Receptor, Mouse	1
PRGR_RABIT	P06186	CHEMBL3456	Progesterone Receptor, Rabit	1
PRGR_RAT	Q63449	CHEMBL2596	Progesterone Receptor, Rat	1
S5A1_RAT	P24008	CHEMBL3422	Steroid 5-alpha-reductase 1, Rat	1
S5A2_RAT	P31214	CHEMBL5099	Steroid 5-alpha-reductase 2, Rat	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	1
THA_HUMAN	P10827	CHEMBL1860	Thyroid Hormone Receptor Alpha, Human	1
THB_HUMAN	P10828	CHEMBL1947	Thyroid Hormone Receptor Beta-1, Human	1
VP16_HHV11	P06492	CHEMBL4218	Alpha Trans-inducing Protein (VP16), Hhv11	1
Z100081	Z100081	CHEMBL613107	PBMC (Peripheral Blood Mononuclear Cells)	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1
Z80156	Z80156	CHEMBL383	HL-60 (Promyeloblast Leukemia Cells)	1
Z80491	Z80491	CHEMBL614163	SK-N-MC (Neuroepithelioma Cells)	1
Z80682	Z80682	CHEMBL392	A549 (Lung Carcinoma Cells)	1
Z80951	Z80951	CHEMBL614822	NIH3T3 (Fibroblasts)	1
Z80954	Z80954	CHEMBL614071	HFF (Foreskin Fibroblasts)	1
Z81011	Z81011	CHEMBL614840	Human Cell Lines	1
Z81247	Z81247	CHEMBL399	HeLa (Cervical Adenocarcinoma Cells)	1