UCSF

Steroid 5-alpha-reductase 2, Rat (541 Compounds)

Swissprot:
S5A2_RAT
Stitch:
S5A2_RAT
UniProt:
P31214
ChEMBL:
CHEMBL5099
PDB:
Srd5a2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 541 27 5 5
Binding ≤ 1μM 507 24 2 2
Functional ≤ 10μM 5 1 1 1

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
S5A2_HUMAN P31213 CHEMBL1856 Steroid 5-alpha-reductase 2, Human 970 12 5 6
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
S5A1_RAT P24008 CHEMBL3422 Steroid 5-alpha-reductase 1, Rat 544 27 5 5

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
S5A2-1-E Steroid 5-alpha-reductase 2 (cluster #1 Of 2), Eukaryotic 1,062 33 6 6
S5A2-2-E Steroid 5-alpha-reductase 2 (cluster #2 Of 2), Eukaryotic 416 9 3 5
Uniprot Swissprot Chembl Description Number Shared
S5A1_RAT P24008 CHEMBL3422 Steroid 5-alpha-reductase 1, Rat 536
S5A2_HUMAN P31213 CHEMBL1856 Steroid 5-alpha-reductase 2, Human 98
S5A1_HUMAN P18405 CHEMBL1787 Steroid 5-alpha-reductase 1, Human 86
3BHS1_HUMAN P14060 CHEMBL1958 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type I, Human 20
3BHS2_HUMAN P26439 CHEMBL3670 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human 20
3BHS7_HUMAN Q9H2F3 CHEMBL3600 3-beta-hydroxysteroid Dehydrogenase Type VII, Human 16
3BHS2_RAT P22072 CHEMBL4821 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Rat 13
3BHS5_RAT P27364 CHEMBL4490 3-beta-hydroxysteroid Dehydrogenase Type III, Rat 13
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 2
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 2
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 2
ANDR_MOUSE P19091 CHEMBL3056 Androgen Receptor, Mouse 1
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 1
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 1
ESR1_RAT P06211 CHEMBL2724 Estrogen Receptor Alpha, Rat 1
ESR2_RAT Q62986 CHEMBL3021 Estrogen Receptor Beta, Rat 1
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 1
MCR_HUMAN P08235 CHEMBL1994 Mineralocorticoid Receptor, Human 1
PRGR_CHICK P07812 CHEMBL3304 Progesterone Receptor, Chick 1
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 1
PRGR_RABIT P06186 CHEMBL3456 Progesterone Receptor, Rabit 1
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 1
SHBG_HUMAN P04278 CHEMBL3305 Testis-specific Androgen-binding Protein, Human 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 1

Most Common Rings