ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (82)
Reactome (0)
Related By:
Pathway (0)
Organism (2)
Gene (1)
Org. Clust. (3)
ChEMBL (33)
Rings (12)

Estrogen Receptor Beta, Rat (82 Compounds)

Swissprot:: ESR2_RAT
Stitch:: ESR2_RAT
UniProt:: Q62986
ChEMBL:: CHEMBL3021
PDB:: 1HJ1 (DOCK); 1QKN (DOCK); 2J7X (DOCK); 2J7Y (DOCK); Esr2

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	82	14	11	11
Binding ≤ 1μM	66	14	11	11
Functional ≤ 10μM	4	1	1	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	1,658	73	50	63
ESR2_MOUSE	O08537	CHEMBL2995	Estrogen Receptor Beta, Mouse	38	6	2	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ESR1_RAT	P06211	CHEMBL2724	Estrogen Receptor Alpha, Rat	84	14	11	11

Clustered By Gene (0)

Clustered By Organism (3)

Code	Description	Substances	Purchasable	Natural	In Man
ESR2-1-E	Estrogen Receptor Beta (cluster #1 Of 4), Eukaryotic	1,119	49	36	52
ESR2-2-E	Estrogen Receptor Beta (cluster #2 Of 4), Eukaryotic	211	12	10	6
ESR2-3-E	Estrogen Receptor Beta (cluster #3 Of 4), Eukaryotic	87	7	1	4
ESR2-4-E	Estrogen Receptor Beta (cluster #4 Of 4), Eukaryotic	321	16	12	14

Uniprot	Swissprot	Chembl	Description	Number Shared
ESR1_RAT	P06211	CHEMBL2724	Estrogen Receptor Alpha, Rat	81
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	27
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	24
ESR1_MOUSE	P19785	CHEMBL3065	Estrogen Receptor Alpha, Mouse	9
ESR2_MOUSE	O08537	CHEMBL2995	Estrogen Receptor Beta, Mouse	9
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	3
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	3
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	2
EBP_HUMAN	Q15125	CHEMBL4931	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human	2
PLD1_HUMAN	Q13393	CHEMBL2536	Phospholipase D1, Human	2
PLD2_HUMAN	O14939	CHEMBL2734	Phospholipase D2, Human	2
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	2
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	1
ANDR_MOUSE	P19091	CHEMBL3056	Androgen Receptor, Mouse	1
ERR1_HUMAN	P11474	CHEMBL3429	Estrogen-related Receptor Alpha, Human	1
ERR2_HUMAN	O95718	CHEMBL3751	Estrogen-related Receptor Beta, Human	1
ERR3_HUMAN	P62508	CHEMBL4245	Estrogen-related Receptor Gamma, Human	1
ESR1_BOVIN	P49884	CHEMBL2930	Estrogen Receptor Alpha, Bovin	1
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	1
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	1
GPER_HUMAN	Q99527	CHEMBL5872	G-protein Coupled Estrogen Receptor 1, Human	1
MCR_HUMAN	P08235	CHEMBL1994	Mineralocorticoid Receptor, Human	1
PRGR_CHICK	P07812	CHEMBL3304	Progesterone Receptor, Chick	1
PRGR_RABIT	P06186	CHEMBL3456	Progesterone Receptor, Rabit	1
S5A1_RAT	P24008	CHEMBL3422	Steroid 5-alpha-reductase 1, Rat	1
S5A2_RAT	P31214	CHEMBL5099	Steroid 5-alpha-reductase 2, Rat	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
SHBG_HUMAN	P04278	CHEMBL3305	Testis-specific Androgen-binding Protein, Human	1
Z80224	Z80224	CHEMBL387	MCF7 (Breast Carcinoma Cells)	1
Z80226	Z80226	CHEMBL614323	MCF7-2A	1
Z80475	Z80475	CHEMBL613834	SK-BR-3 (Breast Adenocarcinoma)	1
Z81068	Z81068	CHEMBL614649	Ishikawa (Uterine Carcinoma Cells)	1
Z81247	Z81247	CHEMBL399	HeLa (Cervical Adenocarcinoma Cells)	1