UCSF

Estrogen-related Receptor Alpha, Human (41 Compounds)

Swissprot:
ERR1_HUMAN
Stitch:
ERR1_HUMAN
UniProt:
P11474
ChEMBL:
CHEMBL3429
Reactome:
REACT_15525
REACT_116145
REACT_200608
PDB:
1XB7 (DOCK)
2PJL (DOCK)
3D24 (DOCK)
3K6P (DOCK)
ESRRA

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 41 2 3 3
Binding ≤ 1μM 30 2 3 3
Functional ≤ 10μM 41 1 2 2

Reactome Network (3)

Reactome ID Description Species
REACT_15525 Nuclear Receptor transcription pathway Homo sapiens
REACT_116145 PPARA activates gene expression Homo sapiens
REACT_200608 Transcriptional activation of mitochondrial biogenesis Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 1
ERR2_HUMAN O95718 CHEMBL3751 Estrogen-related Receptor Beta, Human 22
ERR3_HUMAN P62508 CHEMBL4245 Estrogen-related Receptor Gamma, Human 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 9
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 9
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ERR2_HUMAN O95718 CHEMBL3751 Estrogen-related Receptor Beta, Human 21 2 2 2
ERR3_HUMAN P62508 CHEMBL4245 Estrogen-related Receptor Gamma, Human 13 4 2 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ERR2_HUMAN O95718 CHEMBL3751 Estrogen-related Receptor Beta, Human 22
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 8
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 8
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 1
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 1
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 1
DHB1_HUMAN P14061 CHEMBL3181 Estradiol 17-beta-dehydrogenase 1, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
ERR3_HUMAN P62508 CHEMBL4245 Estrogen-related Receptor Gamma, Human 1
ESR1_BOVIN P49884 CHEMBL2930 Estrogen Receptor Alpha, Bovin 1
ESR1_MOUSE P19785 CHEMBL3065 Estrogen Receptor Alpha, Mouse 1
ESR1_RAT P06211 CHEMBL2724 Estrogen Receptor Alpha, Rat 1
ESR2_MOUSE O08537 CHEMBL2995 Estrogen Receptor Beta, Mouse 1
ESR2_RAT Q62986 CHEMBL3021 Estrogen Receptor Beta, Rat 1
GPER_HUMAN Q99527 CHEMBL5872 G-protein Coupled Estrogen Receptor 1, Human 1
MGA_HUMAN O43451 CHEMBL2074 Maltase-glucoamylase, Human 1
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 1
SHBG_HUMAN P04278 CHEMBL3305 Testis-specific Androgen-binding Protein, Human 1
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1
Z80226 Z80226 CHEMBL614323 MCF7-2A 1
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 1
Z81068 Z81068 CHEMBL614649 Ishikawa (Uterine Carcinoma Cells) 1
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 1