Names
Compounds (111)
Reactome (2)
Related By:
Pathway (0)
Organism (-1)
Gene (-1)
Org. Clust. (-1)
ChEMBL (38)
Rings (14)

G-protein Coupled Bile Acid Receptor 1, Human (111 Compounds)

Swissprot:: GPBAR_HUMAN
Stitch:: GPBAR_HUMAN
UniProt:: Q8TDU6
ChEMBL:: CHEMBL5409
Reactome:: REACT_14828; REACT_19327
PDB:: GPBAR1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Functional ≤ 10μM	111	30	32	13

Reactome ID	Description	Species
REACT_14828	Class A/1 (Rhodopsin-like receptors)	Homo sapiens
REACT_19327	G alpha (s) signalling events	Homo sapiens

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
NR1H4_HUMAN	Q96RI1	CHEMBL2047	Bile Acid Receptor FXR, Human	23
GPBAR_MOUSE	Q80SS6	CHEMBL1255150	G-protein Coupled Bile Acid Receptor 1, Mouse	17
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	3
Z50607	Z50607	CHEMBL378	Human Immunodeficiency Virus 1	3
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	2
Z50420	Z50420	CHEMBL612851	Trypanosoma Brucei Brucei	2
Z50602	Z50602	CHEMBL377	Human Herpesvirus 1	2
Z50652	Z50652	CHEMBL613740	Influenza A Virus	2
Z80928	Z80928	CHEMBL394	HCT-116 (Colon Carcinoma Cells)	2
Z81252	Z81252	CHEMBL400	MDA-MB-231 (Breast Adenocarcinoma Cells)	2
ANDR_RAT	P15207	CHEMBL3072	Androgen Receptor, Rat	1
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	1
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	1
MCR_HUMAN	P08235	CHEMBL1994	Mineralocorticoid Receptor, Human	1
NTCP_RAT	P26435	CHEMBL4847	Bile Acid Transporter, Rat	1
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	1
SHBG_HUMAN	P04278	CHEMBL3305	Testis-specific Androgen-binding Protein, Human	1
SHBG_RAT	P08689	CHEMBL4932	Testis-specific Androgen-binding Protein, Rat	1
Z100499	Z100499	CHEMBL612575	SARS Coronavirus	1
Z103202	Z103202	CHEMBL1075387	8505C	1
Z103205	Z103205	CHEMBL1075390	A431	1
Z50418	Z50418	CHEMBL612849	Trypanosoma Brucei	1
Z50459	Z50459	CHEMBL367	Leishmania Donovani	1
Z50466	Z50466	CHEMBL368	Trypanosoma Cruzi	1
Z50472	Z50472	CHEMBL612888	Toxoplasma Gondii	1
Z50573	Z50573	CHEMBL613478	Xenopus Laevis	1
Z50636	Z50636	CHEMBL613725	Sindbis Virus	1
Z80178	Z80178	CHEMBL614040	J774.A1 (Macrophage Cells)	1
Z80186	Z80186	CHEMBL385	K562 (Erythroleukemia Cells)	1
Z80482	Z80482	CHEMBL614917	SK-MEL-2 (Melanoma Cells)	1
Z80526	Z80526	CHEMBL612544	SW480 (Colon Adenocarcinoma Cells)	1
Z80682	Z80682	CHEMBL392	A549 (Lung Carcinoma Cells)	1
Z80712	Z80712	CHEMBL614361	T47D (Breast Carcinoma Cells)	1
Z80897	Z80897	CHEMBL614806	H9 (T-lymphoid Cells)	1
Z81020	Z81020	CHEMBL395	HepG2 (Hepatoblastoma Cells)	1
Z81034	Z81034	CHEMBL614004	A2780 (Ovarian Carcinoma Cells)	1
Z81072	Z81072	CHEMBL397	Jurkat (Acute Leukemic T-cells)	1
Z81247	Z81247	CHEMBL399	HeLa (Cervical Adenocarcinoma Cells)	1