UCSF

Pregnane X Receptor, Human (39 Compounds)

Swissprot:
NR1I2_HUMAN
Stitch:
NR1I2_HUMAN
UniProt:
O75469
ChEMBL:
CHEMBL3401
PDB:
1ILG (DOCK)
1ILH (DOCK)
1M13 (DOCK)
1NRL (DOCK)
1SKX (DOCK)
2O9I (DOCK)
2QNV (DOCK)
3CTB (DOCK)
3HVL (DOCK)
3R8D (DOCK)
NR1I2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 39 9 2 2
Binding ≤ 1μM 25 8 1 1
Functional ≤ 10μM 43 2 0 0

Reactome Network (0)

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
NR1I2-1-E Pregnane X Receptor (cluster #1 Of 3), Eukaryotic 32 3 1 1
NR1I2-2-E Pregnane X Receptor (cluster #2 Of 3), Eukaryotic 6 6 1 1
NR1I2-3-E Pregnane X Receptor (cluster #3 Of 3), Eukaryotic 1 0 0 0
Uniprot Swissprot Chembl Description Number Shared
DHI1_HUMAN P28845 CHEMBL4235 11-beta-hydroxysteroid Dehydrogenase 1, Human 8
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 7
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 6
DHI1_MOUSE P50172 CHEMBL3910 11-beta-hydroxysteroid Dehydrogenase 1, Mouse 6
MCR_HUMAN P08235 CHEMBL1994 Mineralocorticoid Receptor, Human 5
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 5
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 4
NR1H2_HUMAN P55055 CHEMBL4093 LXR-beta, Human 4
NR1H3_HUMAN Q13133 CHEMBL2808 LXR-alpha, Human 4
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2
BRS3_HUMAN P32247 CHEMBL4080 Bombesin Like Receptor 3, Human 1
BRS3_MOUSE O54798 CHEMBL1075140 Bombesin Receptor Subtype-3, Mouse 1
BRS3_RAT Q8K418 CHEMBL1075111 Bombesin Receptor Subtype-3, Rat 1
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 1
CNR1_RAT P20272 CHEMBL3571 Cannabinoid CB1 Receptor, Rat 1
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 1
CNR2_RAT Q9QZN9 CHEMBL2470 Cannabinoid CB2 Receptor, Rat 1
GRPR_HUMAN P30550 CHEMBL4959 Gastrin Releasing Peptide Receptor, Human 1
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 1
NMBR_HUMAN P28336 CHEMBL3636 Neuromedin B Receptor, Human 1
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 1
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 1

Most Common Rings