Annotation Type | Substances | Purchasable | Natural | In Man |
---|---|---|---|---|
Binding ≤ 10μM | 442 | 4 | 4 | 2 |
Binding ≤ 1μM | 398 | 4 | 3 | 2 |
Functional ≤ 10μM | 336 | 2 | 4 | 1 |
Reactome ID | Description | Species |
---|---|---|
REACT_15525 | Nuclear Receptor transcription pathway | Homo sapiens |
Uniprot | Swissprot | Chembl | Description | Number Shared |
---|---|---|---|---|
ANDR_HUMAN | P10275 | CHEMBL1871 | Androgen Receptor, Human | 1 |
PPARA_HUMAN | Q07869 | CHEMBL239 | Peroxisome Proliferator-activated Receptor Alpha, Human | 19 |
PPARD_HUMAN | Q03181 | CHEMBL3979 | Peroxisome Proliferator-activated Receptor Delta, Human | 21 |
PPARG_HUMAN | P37231 | CHEMBL235 | Peroxisome Proliferator-activated Receptor Gamma, Human | 18 |
UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
---|---|---|---|---|---|---|---|
NR1H3_HUMAN | Q13133 | CHEMBL2808 | LXR-alpha, Human | 485 | 14 | 11 | 3 |
NR1H4_HUMAN | Q96RI1 | CHEMBL2047 | Bile Acid Receptor FXR, Human | 372 | 7 | 7 | 3 |
Code | Description | Substances | Purchasable | Natural | In Man |
---|---|---|---|---|---|
NR1H2-1-E | LXR-beta (cluster #1 Of 3), Eukaryotic | 378 | 2 | 3 | 2 |
NR1H2-2-E | LXR-beta (cluster #2 Of 3), Eukaryotic | 67 | 3 | 0 | 0 |
NR1H2-3-E | LXR-beta (cluster #3 Of 3), Eukaryotic | 1 | 0 | 1 | 0 |
Uniprot | Swissprot | Chembl | Description | Number Shared |
---|---|---|---|---|
NR1H3_HUMAN | Q13133 | CHEMBL2808 | LXR-alpha, Human | 471 |
Z80548 | Z80548 | CHEMBL614245 | THP-1 (Acute Monocytic Leukemia Cells) | 33 |
PPARD_HUMAN | Q03181 | CHEMBL3979 | Peroxisome Proliferator-activated Receptor Delta, Human | 21 |
PPARA_HUMAN | Q07869 | CHEMBL239 | Peroxisome Proliferator-activated Receptor Alpha, Human | 19 |
PPARG_HUMAN | P37231 | CHEMBL235 | Peroxisome Proliferator-activated Receptor Gamma, Human | 17 |
Z81020 | Z81020 | CHEMBL395 | HepG2 (Hepatoblastoma Cells) | 14 |
Z81244 | Z81244 | CHEMBL614123 | J774 (Macrophage Cells) | 5 |
NR1I2_HUMAN | O75469 | CHEMBL3401 | Pregnane X Receptor, Human | 4 |
Z80178 | Z80178 | CHEMBL614040 | J774.A1 (Macrophage Cells) | 4 |
Z50594 | Z50594 | CHEMBL375 | Mus Musculus | 3 |
GCR_HUMAN | P04150 | CHEMBL2034 | Glucocorticoid Receptor, Human | 2 |
Z80169 | Z80169 | CHEMBL614039 | Huh-7 (Hepatocellular Carcinoma) | 2 |
ANDR_HUMAN | P10275 | CHEMBL1871 | Androgen Receptor, Human | 1 |
Z80418 | Z80418 | CHEMBL612557 | RAW264.7 (Monocytic-macrophage Leukemia Cells) | 1 |