UCSF

Protein Farnesyltransferase Beta Subunit, Mouse (10 Compounds)

Swissprot:
FNTB_MOUSE
Stitch:
FNTB_MOUSE
UniProt:
Q8K2I1
ChEMBL:
CHEMBL2631
Reactome:
REACT_188266
PDB:
3PZ4 (DOCK)
Fntb

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 10 0 0 0
Binding ≤ 1μM 5 0 0 0
Functional ≤ 10μM 120 2 1 2

Reactome Network (1)

Reactome ID Description Species
REACT_188266 Inactivation, recovery and regulation of the phototransduction cascade Mus musculus
Uniprot Swissprot Chembl Description Number Shared
FNTA_MOUSE Q61239 CHEMBL2153 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse 130
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
FNTB_BOVIN P49355 CHEMBL4671 Protein Farnesyltransferase Beta Subunit, Bovin 649 6 4 5
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 1,846 10 4 5
FNTB_RAT Q02293 CHEMBL4890 Protein Farnesyltransferase Beta Subunit, Rat 258 1 0 2
FNTB_YEAST P22007 CHEMBL4122 Protein Farnesyltransferase Beta Subunit, Yeast 62 1 1 1

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
FNTB-1-E Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic 2,600 12 6 7
FNTB-1-F Protein Farnesyltransferase Beta Subunit (cluster #1 Of 2), Fungal 51 0 0 0
FNTB-2-E Protein Farnesyltransferase Beta Subunit (cluster #2 Of 3), Eukaryotic 42 2 0 0
FNTB-2-F Protein Farnesyltransferase Beta Subunit (cluster #2 Of 2), Fungal 11 1 1 1
FNTB-3-E Protein Farnesyltransferase Beta Subunit (cluster #3 Of 3), Eukaryotic 52 0 1 0
Uniprot Swissprot Chembl Description Number Shared
FNTA_MOUSE Q61239 CHEMBL2153 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse 130
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 76
FNTA_HUMAN P49354 CHEMBL271 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human 12
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 12
PGTB1_MOUSE Q8BUY9 CHEMBL2295 Geranylgeranyl Transferase Type I Beta Subunit, Mouse 3
FNTA_BOVIN P29702 CHEMBL2377 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin 1
FNTB_BOVIN P49355 CHEMBL4671 Protein Farnesyltransferase Beta Subunit, Bovin 1
PGTB1_BOVIN Q5EAD5 CHEMBL4347 Geranylgeranyl Transferase Type I Beta Subunit, Bovin 1
RASH_HUMAN P01112 CHEMBL2167 Transforming Protein P21/H-Ras-1, Human 1
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 1
Z80106 Z80106 CHEMBL614563 COS-1 (Kidney Cells) 1
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 1
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 1
Z81285 Z81285 CHEMBL615000 NIH-H Cell Line 1
Z81286 Z81286 CHEMBL615001 NIH-K Cell Line 1