ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (668)
Reactome (0)
Related By:
Pathway (0)
Organism (4)
Gene (0)
Org. Clust. (4)
ChEMBL (20)
Rings (9)

Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin (668 Compounds)

Swissprot:: FNTA_BOVIN
Stitch:: FNTA_BOVIN
UniProt:: P29702
ChEMBL:: CHEMBL2377
PDB:: FNTA

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	668	6	4	5
Binding ≤ 1μM	624	6	2	5
Functional ≤ 10μM	22	0	0	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
FNTA_HUMAN	P49354	CHEMBL271	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	1,900	11	6	5
FNTA_MOUSE	Q61239	CHEMBL2153	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse	14	0	0	0
FNTA_RAT	Q04631	CHEMBL4432	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat	322	2	1	4
FNTA_YEAST	P29703	CHEMBL2406	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Yeast	67	1	1	1

Clustered By Gene (0)

Clustered By Organism (4)

Code	Description	Substances	Purchasable	Natural	In Man
FNTA-1-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic	2,644	14	6	7
FNTA-1-F	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 2), Fungal	51	0	0	0
FNTA-2-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #2 Of 3), Eukaryotic	54	2	2	0
FNTA-2-F	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #2 Of 2), Fungal	16	1	1	1
FNTA-3-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #3 Of 3), Eukaryotic	52	0	1	0

Uniprot	Swissprot	Chembl	Description	Number Shared
FNTB_BOVIN	P49355	CHEMBL4671	Protein Farnesyltransferase Beta Subunit, Bovin	654
PGTB1_BOVIN	Q5EAD5	CHEMBL4347	Geranylgeranyl Transferase Type I Beta Subunit, Bovin	206
PGTB1_HUMAN	P53609	CHEMBL4135	Geranylgeranyl Transferase Type I Beta Subunit, Human	89
FNTA_HUMAN	P49354	CHEMBL271	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	70
FNTA_RAT	Q04631	CHEMBL4432	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat	64
FNTB_HUMAN	P49356	CHEMBL272	Protein Farnesyltransferase Beta Subunit, Human	50
FDFT_RAT	Q02769	CHEMBL3815	Squalene Synthetase, Rat	12
FNTB_RAT	Q02293	CHEMBL4890	Protein Farnesyltransferase Beta Subunit, Rat	4
FNTA_YEAST	P29703	CHEMBL2406	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Yeast	2
FNTB_YEAST	P22007	CHEMBL4122	Protein Farnesyltransferase Beta Subunit, Yeast	2
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	1
FNTA_MOUSE	Q61239	CHEMBL2153	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse	1
FNTB_MOUSE	Q8K2I1	CHEMBL2631	Protein Farnesyltransferase Beta Subunit, Mouse	1
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
Q5EI73_PLAFA	Q5EI73	CHEMBL4737	Protein Farnesyltransferase Alpha Subunit, Plafa	1
Q5EI74_PLAFA	Q5EI74	CHEMBL1741264	Protein Farnesyltransferase Beta Subunit, Plafa	1
Q6IE76_BOVIN	Q6IE76	CHEMBL3605	Squalene Synthetase, Bovin	1
SSR5_HUMAN	P35346	CHEMBL1792	Somatostatin Receptor 5, Human	1
Z80401	Z80401	CHEMBL614241	PSN1	1