UCSF

Geranylgeranyl Transferase Type I Beta Subunit, Human (538 Compounds)

Swissprot:
PGTB1_HUMAN
Stitch:
PGTB1_HUMAN
UniProt:
P53609
ChEMBL:
CHEMBL4135
PDB:
PGGT1B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 538 5 4 5
Binding ≤ 1μM 292 3 3 3
Functional ≤ 10μM 57 0 0 1

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PGTB1_BOVIN Q5EAD5 CHEMBL4347 Geranylgeranyl Transferase Type I Beta Subunit, Bovin 206 1 1 1
PGTB1_MOUSE Q8BUY9 CHEMBL2295 Geranylgeranyl Transferase Type I Beta Subunit, Mouse 7 0 0 0
PGTB1_RAT P53610 CHEMBL3989 Geranylgeranyl Transferase Type I Beta Subunit, Rat 5 0 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PGTB1-1-E Geranylgeranyl Transferase Type I Beta Subunit (cluster #1 Of 2), Eukaryotic 727 6 2 5
PGTB1-2-E Geranylgeranyl Transferase Type I Beta Subunit (cluster #2 Of 2), Eukaryotic 19 0 2 0
Uniprot Swissprot Chembl Description Number Shared
FNTA_HUMAN P49354 CHEMBL271 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human 525
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 452
FNTA_BOVIN P29702 CHEMBL2377 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin 89
FNTB_BOVIN P49355 CHEMBL4671 Protein Farnesyltransferase Beta Subunit, Bovin 89
FNTA_RAT Q04631 CHEMBL4432 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat 44
FNTB_RAT Q02293 CHEMBL4890 Protein Farnesyltransferase Beta Subunit, Rat 41
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 19
PGTB1_BOVIN Q5EAD5 CHEMBL4347 Geranylgeranyl Transferase Type I Beta Subunit, Bovin 10
PGTB1_RAT P53610 CHEMBL3989 Geranylgeranyl Transferase Type I Beta Subunit, Rat 5
Q5EI73_PLAFA Q5EI73 CHEMBL4737 Protein Farnesyltransferase Alpha Subunit, Plafa 5
Q5EI74_PLAFA Q5EI74 CHEMBL1741264 Protein Farnesyltransferase Beta Subunit, Plafa 5
Z80401 Z80401 CHEMBL614241 PSN1 2
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
SSR5_HUMAN P35346 CHEMBL1792 Somatostatin Receptor 5, Human 1
Z80005 Z80005 CHEMBL614077 3T3 (Fibroblast Cells) 1

Most Common Rings