ZINC 12

User Information

Not Authenticated — sign in

Active cart: Temporary Cart (0 items)

Navigation

About
- ZINC
- BCIRC
- Irwin Lab
- Shoichet Lab
- UCSF
- Acknowledgements
- Facts
- Usage
Search
- By:
- Text
- Structure
- Properties
- Catalogs
- ZINC
- Targets
- Rings
- Combination
Subsets
- By:
- Catalog
- Property
- Target
- Ring
- Cart
Help
- Introduction
- FAQ
- Scripting/API
- Quick Search
- Problems
- Filtering
- History
Social
- ZINC Fans
- Decoy Club
- DOCK Fans
- Facebook
- Twitter
- Blog
- Linkedin
Quick Search ZINC ID or SMILES

Names
Compounds (649)
Reactome (1)
Related By:
Pathway (0)
Organism (4)
Gene (0)
Org. Clust. (4)
ChEMBL (20)
Rings (8)

Protein Farnesyltransferase Beta Subunit, Bovin (649 Compounds)

Swissprot:: FNTB_BOVIN
Stitch:: FNTB_BOVIN
UniProt:: P49355
ChEMBL:: CHEMBL4671
Reactome:: REACT_209198
PDB:: FNTB

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	649	6	4	5
Binding ≤ 1μM	616	6	2	5
Functional ≤ 10μM	22	0	0	1

Reactome ID	Description	Species
REACT_209198	Inactivation, recovery and regulation of the phototransduction cascade	Bos taurus

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
FNTB_HUMAN	P49356	CHEMBL272	Protein Farnesyltransferase Beta Subunit, Human	1,846	10	4	5
FNTB_MOUSE	Q8K2I1	CHEMBL2631	Protein Farnesyltransferase Beta Subunit, Mouse	10	0	0	0
FNTB_RAT	Q02293	CHEMBL4890	Protein Farnesyltransferase Beta Subunit, Rat	258	1	0	2
FNTB_YEAST	P22007	CHEMBL4122	Protein Farnesyltransferase Beta Subunit, Yeast	62	1	1	1

Clustered By Gene (0)

Clustered By Organism (4)

Code	Description	Substances	Purchasable	Natural	In Man
FNTB-1-E	Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic	2,600	12	6	7
FNTB-1-F	Protein Farnesyltransferase Beta Subunit (cluster #1 Of 2), Fungal	51	0	0	0
FNTB-2-E	Protein Farnesyltransferase Beta Subunit (cluster #2 Of 3), Eukaryotic	42	2	0	0
FNTB-2-F	Protein Farnesyltransferase Beta Subunit (cluster #2 Of 2), Fungal	11	1	1	1
FNTB-3-E	Protein Farnesyltransferase Beta Subunit (cluster #3 Of 3), Eukaryotic	52	0	1	0

Uniprot	Swissprot	Chembl	Description	Number Shared
FNTA_BOVIN	P29702	CHEMBL2377	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin	654
PGTB1_BOVIN	Q5EAD5	CHEMBL4347	Geranylgeranyl Transferase Type I Beta Subunit, Bovin	187
PGTB1_HUMAN	P53609	CHEMBL4135	Geranylgeranyl Transferase Type I Beta Subunit, Human	89
FNTA_RAT	Q04631	CHEMBL4432	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat	64
FNTA_HUMAN	P49354	CHEMBL271	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	51
FNTB_HUMAN	P49356	CHEMBL272	Protein Farnesyltransferase Beta Subunit, Human	31
FDFT_RAT	Q02769	CHEMBL3815	Squalene Synthetase, Rat	12
FNTB_RAT	Q02293	CHEMBL4890	Protein Farnesyltransferase Beta Subunit, Rat	4
FNTA_YEAST	P29703	CHEMBL2406	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Yeast	2
FNTB_YEAST	P22007	CHEMBL4122	Protein Farnesyltransferase Beta Subunit, Yeast	2
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	1
FNTA_MOUSE	Q61239	CHEMBL2153	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse	1
FNTB_MOUSE	Q8K2I1	CHEMBL2631	Protein Farnesyltransferase Beta Subunit, Mouse	1
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
Q5EI73_PLAFA	Q5EI73	CHEMBL4737	Protein Farnesyltransferase Alpha Subunit, Plafa	1
Q5EI74_PLAFA	Q5EI74	CHEMBL1741264	Protein Farnesyltransferase Beta Subunit, Plafa	1
Q6IE76_BOVIN	Q6IE76	CHEMBL3605	Squalene Synthetase, Bovin	1
SSR5_HUMAN	P35346	CHEMBL1792	Somatostatin Receptor 5, Human	1
Z80401	Z80401	CHEMBL614241	PSN1	1