UCSF

Integrin Beta-2, Human (207 Compounds)

Swissprot:
ITB2_HUMAN
Stitch:
ITB2_HUMAN
UniProt:
P05107
ChEMBL:
CHEMBL3631
Reactome:
REACT_12051
REACT_11152
REACT_13552
REACT_6894
PDB:
1JX3 (DOCK)
1L3Y (DOCK)
1YUK (DOCK)
2JF1 (DOCK)
2P26 (DOCK)
2P28 (DOCK)
2V7D (DOCK)
3K6S (DOCK)
3K71 (DOCK)
3K72 (DOCK)
ITGB2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 207 5 0 0
Binding ≤ 1μM 179 2 0 0
Functional ≤ 10μM 87 4 0 0
Uniprot Swissprot Chembl Description Number Shared
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 284

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Uniprot Swissprot Chembl Description Number Shared
ICAM1_HUMAN P05362 CHEMBL3070 Intercellular Adhesion Molecule-1, Human 91
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 284

Integrin cell surface interactions

Uniprot Swissprot Chembl Description Number Shared
ICAM1_HUMAN P05362 CHEMBL3070 Intercellular Adhesion Molecule-1, Human 91
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 284
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 249 1 0 0
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1,479 4 8 8
ITB5_HUMAN P18084 CHEMBL2600 Integrin Beta-5, Human 280 0 0 1
ITB6_HUMAN P18564 CHEMBL4876 Integrin Beta-6, Human 213 0 0 0
ITB7_HUMAN P26010 CHEMBL2979 Integrin Beta-7, Human 355 9 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 284
ICAM1_HUMAN P05362 CHEMBL3070 Intercellular Adhesion Molecule-1, Human 91
Z80185 Z80185 CHEMBL613833 JY (EBV-transformed B-lymphoblastoid Cells) 14
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 11
Z81338 Z81338 CHEMBL614309 T-cells 11
Z80885 Z80885 CHEMBL614507 BEND (Brain Endothelial Cells) 2
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 1
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 1