UCSF

Integrin Beta-5, Human (280 Compounds)

Swissprot:
ITB5_HUMAN
Stitch:
ITB5_HUMAN
UniProt:
P18084
ChEMBL:
CHEMBL2600
Reactome:
REACT_111174
REACT_163906
REACT_13552
REACT_150331
REACT_20558
REACT_163942
PDB:
ITGB5

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 280 0 0 1
Binding ≤ 1μM 255 0 0 1
Functional ≤ 10μM 18 0 0 0

Reactome Network (6)

Reactome ID Description Species
REACT_111174 Cross-presentation of particulate exogenous antigens (phagosomes) Homo sapiens
REACT_163906 ECM proteoglycans Homo sapiens
REACT_13552 Integrin cell surface interactions Homo sapiens
REACT_150331 Molecules associated with elastic fibres Homo sapiens
REACT_20558 Smooth Muscle Contraction Homo sapiens
REACT_163942 Syndecan interactions Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 258

ECM proteoglycans

Uniprot Swissprot Chembl Description Number Shared
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 163
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 258
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 70
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 157
ITB6_HUMAN P18564 CHEMBL4876 Integrin Beta-6, Human 98

Integrin cell surface interactions

Uniprot Swissprot Chembl Description Number Shared
FIBB_HUMAN P02675 CHEMBL2048 Fibrinogen Beta Chain, Human 1
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 163
ITA5_HUMAN P08648 CHEMBL3955 Fibronectin Receptor Alpha, Human 31
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 258
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 70
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 157
ITB6_HUMAN P18564 CHEMBL4876 Integrin Beta-6, Human 98

Molecules associated with elastic fibres

Uniprot Swissprot Chembl Description Number Shared
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 258
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 70
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 157
ITB6_HUMAN P18564 CHEMBL4876 Integrin Beta-6, Human 98

Syndecan interactions

Uniprot Swissprot Chembl Description Number Shared
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 258
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 70
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 157
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 249 1 0 0
ITB2_HUMAN P05107 CHEMBL3631 Integrin Beta-2, Human 207 5 0 0
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 1,479 4 8 8
ITB6_HUMAN P18564 CHEMBL4876 Integrin Beta-6, Human 213 0 0 0
ITB7_HUMAN P26010 CHEMBL2979 Integrin Beta-7, Human 355 9 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z104292 Z104292 CHEMBL1907598 Integrin Alpha-V/beta-3 278
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 258
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 163
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 157
ITB6_HUMAN P18564 CHEMBL4876 Integrin Beta-6, Human 98
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 70
ITA5_HUMAN P08648 CHEMBL3955 Fibronectin Receptor Alpha, Human 31
FIBB_HUMAN P02675 CHEMBL2048 Fibrinogen Beta Chain, Human 1

Most Common Rings