UCSF

Intercellular Adhesion Molecule-1, Human (330 Compounds)

Swissprot:
ICAM1_HUMAN
Stitch:
ICAM1_HUMAN
UniProt:
P05362
ChEMBL:
CHEMBL3070
Reactome:
REACT_11152
REACT_13552
REACT_25078
PDB:
1D3E (DOCK)
1D3I (DOCK)
1D3L (DOCK)
1IAM (DOCK)
1IC1 (DOCK)
1IJ4 (DOCK)
1MQ8 (DOCK)
1P53 (DOCK)
1Z7Z (DOCK)
2OZ4 (DOCK)
3TCX (DOCK)
ICAM1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 330 21 0 0
Binding ≤ 1μM 261 10 0 0
Functional ≤ 10μM 66 2 1 1

Reactome Network (3)

Reactome ID Description Species
REACT_11152 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens
REACT_13552 Integrin cell surface interactions Homo sapiens
REACT_25078 Interferon gamma signaling Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 258
ITB2_HUMAN P05107 CHEMBL3631 Integrin Beta-2, Human 91
VCAM1_HUMAN P19320 CHEMBL3735 Vascular Cell Adhesion Protein 1, Human 36

Integrin cell surface interactions

Uniprot Swissprot Chembl Description Number Shared
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 258
ITB2_HUMAN P05107 CHEMBL3631 Integrin Beta-2, Human 91
VCAM1_HUMAN P19320 CHEMBL3735 Vascular Cell Adhesion Protein 1, Human 36

Interferon gamma signaling

Uniprot Swissprot Chembl Description Number Shared
VCAM1_HUMAN P19320 CHEMBL3735 Vascular Cell Adhesion Protein 1, Human 36

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 258
LYAM2_HUMAN P16581 CHEMBL3890 Selectin E, Human 117
ITB2_HUMAN P05107 CHEMBL3631 Integrin Beta-2, Human 91
VCAM1_HUMAN P19320 CHEMBL3735 Vascular Cell Adhesion Protein 1, Human 36
Z80185 Z80185 CHEMBL613833 JY (EBV-transformed B-lymphoblastoid Cells) 14
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 3
HMDH_HUMAN P04035 CHEMBL402 HMG-CoA Reductase, Human 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 1
Z80952 Z80952 CHEMBL614662 HES 1
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 1