UCSF

HMG-CoA Reductase, Human (232 Compounds)

Swissprot:
HMDH_HUMAN
Stitch:
HMDH_HUMAN
UniProt:
P04035
ChEMBL:
CHEMBL402
PDB:
1DQ8 (DOCK)
1DQ9 (DOCK)
1DQA (DOCK)
1HW8 (DOCK)
1HW9 (DOCK)
1HWI (DOCK)
1HWJ (DOCK)
1HWK (DOCK)
1HWL (DOCK)
2Q1L (DOCK)
2Q6B (DOCK)
2Q6C (DOCK)
2R4F (DOCK)
3BGL (DOCK)
3CCT (DOCK)
3CCW (DOCK)
3CCZ (DOCK)
3CD0 (DOCK)
3CD5 (DOCK)
3CD7 (DOCK)
3CDA (DOCK)
3CDB (DOCK)
HMGCR

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 232 23 14 12
Binding ≤ 1μM 201 21 11 11
Functional ≤ 10μM 36 2 2 2

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
HMDH_MESAU P09610 CHEMBL1075267 3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Mesau 3 0 0 0
HMDH_MOUSE Q01237 CHEMBL2764 HMG-CoA Reductase, Mouse 3 1 1 1
HMDH_RAT P51639 CHEMBL3247 HMG-CoA Reductase, Rat 925 28 10 10

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
HMDH-1-E HMG-CoA Reductase (cluster #1 Of 2), Eukaryotic 535 36 15 13
HMDH-2-E HMG-CoA Reductase (cluster #2 Of 2), Eukaryotic 580 10 8 8
Uniprot Swissprot Chembl Description Number Shared
HMDH_RAT P51639 CHEMBL3247 HMG-CoA Reductase, Rat 80
CP51A_RAT Q64654 CHEMBL4981 Cytochrome P450 51, Rat 8
Z80952 Z80952 CHEMBL614662 HES 5
HMDH_MESAU P09610 CHEMBL1075267 3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Mesau 3
HMDH_MOUSE Q01237 CHEMBL2764 HMG-CoA Reductase, Mouse 3
Z50590 Z50590 CHEMBL613488 Sus Scrofa 3
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 2
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 1
ICAM1_HUMAN P05362 CHEMBL3070 Intercellular Adhesion Molecule-1, Human 1
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 1
Z81135 Z81135 CHEMBL614793 L6 (Skeletal Muscle Myoblast Cells) 1