UCSF

Cytochrome P450 51, Rat (14 Compounds)

Swissprot:
CP51A_RAT
Stitch:
CP51A_RAT
UniProt:
Q64654
ChEMBL:
CHEMBL4981
Reactome:
REACT_198613
REACT_238041
REACT_252303

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 14 2 3 2
Binding ≤ 1μM 8 1 1 2

Reactome Network (3)

Reactome ID Description Species
REACT_198613 Activation of gene expression by SREBF (SREBP) Rattus norvegicus
REACT_238041 Cholesterol biosynthesis Rattus norvegicus
REACT_252303 Endogenous sterols Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
CP11A_RAT P14137 CHEMBL5246 Cytochrome P450 11A1, Rat 3
CP17A_RAT P11715 CHEMBL4430 Cytochrome P450 17A1, Rat 3
CP7A1_RAT P18125 CHEMBL2339 Cytochrome P450 7A1, Rat 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CP51A_HUMAN Q16850 CHEMBL3849 Cytochrome P450 51, Human 29 11 11 13

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CP51A-1-E Cytochrome P450 51 (cluster #1 Of 2), Eukaryotic 31 12 13 13
CP51A-2-E Cytochrome P450 51 (cluster #2 Of 2), Eukaryotic 10 0 0 0
Uniprot Swissprot Chembl Description Number Shared
HMDH_HUMAN P04035 CHEMBL402 HMG-CoA Reductase, Human 8
CP17A_HUMAN P05093 CHEMBL3522 Cytochrome P450 17A1, Human 4
C11B1_BOVIN P15150 CHEMBL2927 Cytochrome P450 11B1, Bovin 3
CP11A_RAT P14137 CHEMBL5246 Cytochrome P450 11A1, Rat 3
CP17A_RAT P11715 CHEMBL4430 Cytochrome P450 17A1, Rat 3
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 3
CP21A_HUMAN P08686 CHEMBL2759 Cytochrome P450 21, Human 3
CP7A1_RAT P18125 CHEMBL2339 Cytochrome P450 7A1, Rat 3
C11B1_HUMAN P15538 CHEMBL1908 Cytochrome P450 11B1, Human 2
CP51A_HUMAN Q16850 CHEMBL3849 Cytochrome P450 51, Human 2
C11B2_HUMAN P19099 CHEMBL2722 Cytochrome P450 11B2, Human 1
CP24A_HUMAN Q07973 CHEMBL4521 Cytochrome P450 24A1, Human 1
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 1
GNRHR_RAT P30969 CHEMBL3066 Gonadotropin-releasing Hormone Receptor, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1