UCSF

Cytochrome P450 17A1, Rat (324 Compounds)

Swissprot:
CP17A_RAT
Stitch:
CP17A_RAT
UniProt:
P11715
ChEMBL:
CHEMBL4430
Reactome:
REACT_243619
REACT_252303
REACT_234086
PDB:
Cyp17a1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 324 15 6 1
Binding ≤ 1μM 196 3 3 1

Reactome Network (3)

Reactome ID Description Species
REACT_243619 Androgen biosynthesis Rattus norvegicus
REACT_252303 Endogenous sterols Rattus norvegicus
REACT_234086 Glucocorticoid biosynthesis Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
CP11A_RAT P14137 CHEMBL5246 Cytochrome P450 11A1, Rat 3
CP51A_RAT Q64654 CHEMBL4981 Cytochrome P450 51, Rat 3
CP7A1_RAT P18125 CHEMBL2339 Cytochrome P450 7A1, Rat 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CP17A_HUMAN P05093 CHEMBL3522 Cytochrome P450 17A1, Human 690 50 29 14

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CP17A-1-E Cytochrome P450 17A1 (cluster #1 Of 2), Eukaryotic 353 25 13 12
CP17A-2-E Cytochrome P450 17A1 (cluster #2 Of 2), Eukaryotic 435 42 17 2
Uniprot Swissprot Chembl Description Number Shared
CP17A_HUMAN P05093 CHEMBL3522 Cytochrome P450 17A1, Human 245
S5A2_HUMAN P31213 CHEMBL1856 Steroid 5-alpha-reductase 2, Human 36
C11B2_HUMAN P19099 CHEMBL2722 Cytochrome P450 11B2, Human 30
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 28
S5A1_HUMAN P18405 CHEMBL1787 Steroid 5-alpha-reductase 1, Human 28
C11B1_HUMAN P15538 CHEMBL1908 Cytochrome P450 11B1, Human 6
CP11A_BOVIN P00189 CHEMBL4813 Cytochrome P450 11A1, Bovin 4
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A Synthase, Human 4
C11B1_BOVIN P15150 CHEMBL2927 Cytochrome P450 11B1, Bovin 3
CP11A_RAT P14137 CHEMBL5246 Cytochrome P450 11A1, Rat 3
CP21A_HUMAN P08686 CHEMBL2759 Cytochrome P450 21, Human 3
CP51A_RAT Q64654 CHEMBL4981 Cytochrome P450 51, Rat 3
CP7A1_RAT P18125 CHEMBL2339 Cytochrome P450 7A1, Rat 3
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 2
Q64546_RAT Q64546 CHEMBL1687684 Cytochrome P450c11B3, Rat 2
CP24A_HUMAN Q07973 CHEMBL4521 Cytochrome P450 24A1, Human 1
CP51A_HUMAN Q16850 CHEMBL3849 Cytochrome P450 51, Human 1
GNRHR_RAT P30969 CHEMBL3066 Gonadotropin-releasing Hormone Receptor, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1

Most Common Rings