UCSF

Phenylethanolamine N-methyltransferase, Human (202 Compounds)

Swissprot:
PNMT_HUMAN
Stitch:
PNMT_HUMAN
UniProt:
P11086
ChEMBL:
CHEMBL4617
Reactome:
REACT_15551
PDB:
1HNN (DOCK)
1N7I (DOCK)
1N7J (DOCK)
1YZ3 (DOCK)
2AN3 (DOCK)
2AN4 (DOCK)
2AN5 (DOCK)
2G70 (DOCK)
2G71 (DOCK)
2G72 (DOCK)
2G8N (DOCK)
2OBF (DOCK)
2ONY (DOCK)
2ONZ (DOCK)
2OPB (DOCK)
3HCA (DOCK)
3HCB (DOCK)
3HCC (DOCK)
3HCD (DOCK)
3HCE (DOCK)
3HCF (DOCK)
3KPJ (DOCK)
3KPU (DOCK)
3KPV (DOCK)
3KPW (DOCK)
3KPY (DOCK)
3KQM (DOCK)
3KQO (DOCK)
3KQP (DOCK)
3KQQ (DOCK)
3KQS (DOCK)
3KQT (DOCK)
3KQV (DOCK)
3KQW (DOCK)
3KQY (DOCK)
3KR0 (DOCK)
3KR1 (DOCK)
3KR2 (DOCK)
PNMT

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 202 39 4 13
Binding ≤ 1μM 96 26 0 9

Reactome Network (1)

Reactome ID Description Species
REACT_15551 Catecholamine biosynthesis Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 135 47 4 8

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
PNMT-1-E Phenylethanolamine N-methyltransferase (cluster #1 Of 3), Eukaryotic 291 75 8 19
PNMT-2-E Phenylethanolamine N-methyltransferase (cluster #2 Of 3), Eukaryotic 15 4 0 0
PNMT-3-E Phenylethanolamine N-methyltransferase (cluster #3 Of 3), Eukaryotic 16 0 0 0
Uniprot Swissprot Chembl Description Number Shared
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 49
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 25
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 25
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 25
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 19
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 8
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 8
DCAM_HUMAN P17707 CHEMBL4181 S-adenosylmethionine Decarboxylase 1, Human 4