UCSF

Coagulation Factor VII, Human (612 Compounds)

Swissprot:
FA7_HUMAN
Stitch:
FA7_HUMAN
UniProt:
P08709
ChEMBL:
CHEMBL3991
Reactome:
REACT_111118
REACT_1573
REACT_1050
REACT_733
REACT_1906
PDB:
1BF9 (DOCK)
1CVW (DOCK)
1DAN (DOCK)
1DVA (DOCK)
1F7E (DOCK)
1F7M (DOCK)
1FAK (DOCK)
1FF7 (DOCK)
1FFM (DOCK)
1J9C (DOCK)
1JBU (DOCK)
1KLI (DOCK)
1KLJ (DOCK)
1NL8 (DOCK)
1O5D (DOCK)
1QFK (DOCK)
1W0Y (DOCK)
1W2K (DOCK)
1W7X (DOCK)
1W8B (DOCK)
1WQV (DOCK)
1WSS (DOCK)
1WTG (DOCK)
1WUN (DOCK)
1WV7 (DOCK)
1YGC (DOCK)
1Z6J (DOCK)
2A2Q (DOCK)
2AEI (DOCK)
2AER (DOCK)
2B7D (DOCK)
2B8O (DOCK)
2BZ6 (DOCK)
2C4F (DOCK)
2EC9 (DOCK)
2F9B (DOCK)
2FIR (DOCK)
2FLB (DOCK)
2FLR (DOCK)
2PUQ (DOCK)
2ZP0 (DOCK)
2ZWL (DOCK)
2ZZU (DOCK)
3ELA (DOCK)
F7

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 612 0 0 7
Binding ≤ 1μM 508 0 0 6
Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 130
TF_HUMAN P13726 CHEMBL4081 Coagulation Factor III, Human 301

Gamma-carboxylation of protein precursors

Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 130
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 199

Removal of aminoterminal propeptides from gamma-carboxylated proteins

Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 130
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 199

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu

Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 130
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 199
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 4,842 10 8 60
FA11_HUMAN P03951 CHEMBL2820 Coagulation Factor XI, Human 62 0 0 0
FA12_HUMAN P00748 CHEMBL2821 Coagulation Factor XII, Human 8 1 0 0
FA5_HUMAN P12259 CHEMBL3618 Coagulation Factor V, Human 40 6 0 0
FA8_HUMAN P00451 CHEMBL3143 Coagulation Factor VIII, Human 2 2 0 0
FA9_HUMAN P00740 CHEMBL2016 Coagulation Factor IX, Human 255 0 1 5
FAAH1_HUMAN O00519 CHEMBL2243 Anandamide Amidohydrolase, Human 624 36 12 3
FABP4_HUMAN P15090 CHEMBL2083 Fatty Acid Binding Protein Adipocyte, Human 94 16 5 9
FABP5_HUMAN Q01469 CHEMBL3674 Fatty Acid Binding Protein Epidermal, Human 19 6 2 3
FABPH_HUMAN P05413 CHEMBL3344 Fatty Acid Binding Protein Muscle, Human 27 7 2 4
FABPI_HUMAN P12104 CHEMBL4879 Fatty Acid Binding Protein Intestinal, Human 5 4 3 3
FABPL_HUMAN P07148 CHEMBL5421 Fatty Acid-binding Protein, Liver, Human 3 2 1 1
FACE2_HUMAN Q9Y256 CHEMBL3411 Prenyl Protein Specific Protease, Human 2 0 0 0
FADS1_HUMAN O60427 CHEMBL5840 Fatty Acid Desaturase 1, Human 1 0 0 0
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 160 15 6 8
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 57 11 4 5
FAS_HUMAN P49327 CHEMBL4158 Fatty Acid Synthase, Human 42 3 5 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
TF_HUMAN P13726 CHEMBL4081 Coagulation Factor III, Human 301
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 199
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 130
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 69
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 36
TRY3_HUMAN P35030 CHEMBL4551 Trypsin III, Human 30
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 28
TRY1_BOVIN P00760 CHEMBL3769 Trypsin I, Bovin 19
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 19
TPA_HUMAN P00750 CHEMBL1873 Tissue-type Plasminogen Activator, Human 10
PLMN_RAT Q01177 CHEMBL3204 Plasminogen, Rat 7
FA11_HUMAN P03951 CHEMBL2820 Coagulation Factor XI, Human 6
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 5
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 5
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 5
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 5
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 5
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 5
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 5
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 5
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 5
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 5
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 5
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 4
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 3
T2AG_HUMAN P52657 CHEMBL4283 Transcription Initiation Factor IIA Gamma Chain, Human 1