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FAS_HUMAN - Fatty Acid Synthase, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Fatty Acid Synthase, Human (42 Compounds)

Swissprot:
FAS_HUMAN
Stitch:
FAS_HUMAN
UniProt:
P49327
ChEMBL:
CHEMBL4158
Reactome:
REACT_147904
REACT_2122
REACT_1319
REACT_11172
PDB:
1XKT (DOCK)
2CG5 (DOCK)
2JFD (DOCK)
2JFK (DOCK)
2PX6 (DOCK)
3HHD (DOCK)
3TJM (DOCK)
FASN

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 42 3 5 1
Binding ≤ 1μM 28 0 0 0

Reactome Network (4)

Reactome ID Description Species
REACT_147904 Activation of gene expression by SREBF (SREBP) Homo sapiens
REACT_2122 ChREBP activates metabolic gene expression Homo sapiens
REACT_1319 Fatty Acyl-CoA Biosynthesis Homo sapiens
REACT_11172 Vitamin B5 (pantothenate) metabolism Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
FAS_MOUSE P19096 CHEMBL1795189 Fatty Acid Synthase, Mouse 1 0 0 0
FAS_RAT P12785 CHEMBL3783 Fatty Acid Synthase, Rat 22 0 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
FAS-1-E Fatty Acid Synthase (cluster #1 Of 2), Eukaryotic 53 2 4 0
FAS-2-E Fatty Acid Synthase (cluster #2 Of 2), Eukaryotic 9 1 1 1
Uniprot Swissprot Chembl Description Number Shared
FAS_RAT P12785 CHEMBL3783 Fatty Acid Synthase, Rat 2
NANH_CLOPE P10481 CHEMBL5189 Sialidase, Clope 2
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 1
FAS_MOUSE P19096 CHEMBL1795189 Fatty Acid Synthase, Mouse 1
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 1
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1