UCSF

Coagulation Factor IX, Human (255 Compounds)

Swissprot:
FA9_HUMAN
Stitch:
FA9_HUMAN
UniProt:
P00740
ChEMBL:
CHEMBL2016
Reactome:
REACT_1573
REACT_1050
REACT_326
REACT_733
REACT_1906
PDB:
1CFH (DOCK)
1CFI (DOCK)
1EDM (DOCK)
1IXA (DOCK)
1MGX (DOCK)
1NL0 (DOCK)
1RFN (DOCK)
2WPH (DOCK)
2WPI (DOCK)
2WPJ (DOCK)
2WPK (DOCK)
2WPL (DOCK)
2WPM (DOCK)
3KCG (DOCK)
3LC3 (DOCK)
3LC5 (DOCK)
F9

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 255 0 1 5
Binding ≤ 1μM 215 0 0 3
Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 232

Gamma-carboxylation of protein precursors

Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 232
PROC_HUMAN P04070 CHEMBL4444 Vitamin K-dependent Protein C, Human 1
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 15

Intrinsic Pathway

Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 232
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 1
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 15

Removal of aminoterminal propeptides from gamma-carboxylated proteins

Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 232
PROC_HUMAN P04070 CHEMBL4444 Vitamin K-dependent Protein C, Human 1
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 15

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu

Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 232
PROC_HUMAN P04070 CHEMBL4444 Vitamin K-dependent Protein C, Human 1
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 15
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 4,842 10 8 60
FA11_HUMAN P03951 CHEMBL2820 Coagulation Factor XI, Human 62 0 0 0
FA12_HUMAN P00748 CHEMBL2821 Coagulation Factor XII, Human 8 1 0 0
FA5_HUMAN P12259 CHEMBL3618 Coagulation Factor V, Human 40 6 0 0
FA7_HUMAN P08709 CHEMBL3991 Coagulation Factor VII, Human 612 0 0 7
FA8_HUMAN P00451 CHEMBL3143 Coagulation Factor VIII, Human 2 2 0 0
FAAH1_HUMAN O00519 CHEMBL2243 Anandamide Amidohydrolase, Human 624 36 12 3
FABP4_HUMAN P15090 CHEMBL2083 Fatty Acid Binding Protein Adipocyte, Human 94 16 5 9
FABP5_HUMAN Q01469 CHEMBL3674 Fatty Acid Binding Protein Epidermal, Human 19 6 2 3
FABPH_HUMAN P05413 CHEMBL3344 Fatty Acid Binding Protein Muscle, Human 27 7 2 4
FABPI_HUMAN P12104 CHEMBL4879 Fatty Acid Binding Protein Intestinal, Human 5 4 3 3
FABPL_HUMAN P07148 CHEMBL5421 Fatty Acid-binding Protein, Liver, Human 3 2 1 1
FACE2_HUMAN Q9Y256 CHEMBL3411 Prenyl Protein Specific Protease, Human 2 0 0 0
FADS1_HUMAN O60427 CHEMBL5840 Fatty Acid Desaturase 1, Human 1 0 0 0
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 160 15 6 8
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 57 11 4 5
FAS_HUMAN P49327 CHEMBL4158 Fatty Acid Synthase, Human 42 3 5 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 232
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 96
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 19
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 17
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 15
CTRB1_HUMAN P17538 CHEMBL4796 Beta-chymotrypsin, Human 2
FA10_RABIT O19045 CHEMBL5062 Coagulation Factor X, Rabit 1
KLK1_HUMAN P06870 CHEMBL2319 Kallikrein 1, Human 1
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 1
O77669_CANFA O77669 CHEMBL3929 Coagulation Factor X, Canine 1
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 1
PROC_HUMAN P04070 CHEMBL4444 Vitamin K-dependent Protein C, Human 1
TPA_HUMAN P00750 CHEMBL1873 Tissue-type Plasminogen Activator, Human 1
UROK_PIG P04185 CHEMBL1075030 Urokinase-type Plasminogen Activator, Pig 1