UCSF

Kallikrein 1, Human (62 Compounds)

Swissprot:
KLK1_HUMAN
Stitch:
KLK1_HUMAN
UniProt:
P06870
ChEMBL:
CHEMBL2319
Reactome:
REACT_15428
PDB:
1SPJ (DOCK)
KLK1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 62 4 1 7
Binding ≤ 1μM 45 1 1 3

Reactome Network (1)

Reactome ID Description Species
REACT_15428 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
KLK13_HUMAN Q9UKR3 CHEMBL4863 Kallikrein 13, Human 8
KLK2_HUMAN P20151 CHEMBL2442 Kallikrein 2, Human 8
KLK3_HUMAN P07288 CHEMBL2099 Prostate Specific Antigen, Human 8
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 49
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 55
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
KLK10_HUMAN O43240 CHEMBL4180 Kallikrein 10, Human 8 0 0 0
KLK11_HUMAN Q9UBX7 CHEMBL3031 Kallikrein 11, Human 8 0 0 0
KLK12_HUMAN Q9UKR0 CHEMBL4943 Kallikrein 12, Human 8 0 0 0
KLK13_HUMAN Q9UKR3 CHEMBL4863 Kallikrein 13, Human 8 0 0 0
KLK14_HUMAN Q9P0G3 CHEMBL2641 Kallikrein 14, Human 8 0 0 0
KLK15_HUMAN Q9H2R5 CHEMBL2174 Kallikrein 15, Human 8 0 0 0
KLK2_HUMAN P20151 CHEMBL2442 Kallikrein 2, Human 8 0 0 0
KLK3_HUMAN P07288 CHEMBL2099 Prostate Specific Antigen, Human 30 0 0 0
KLK4_HUMAN Q9Y5K2 CHEMBL4446 Kallikrein 4, Human 9 0 0 0
KLK5_HUMAN Q9Y337 CHEMBL4447 Kallikrein 5, Human 8 0 0 0
KLK6_HUMAN Q92876 CHEMBL4448 Kallikrein 6, Human 8 0 0 0
KLK7_HUMAN P49862 CHEMBL2443 Kallikrein 7, Human 8 0 0 0
KLK8_HUMAN O60259 CHEMBL4812 Kallikrein 8, Human 8 0 0 0
KLK9_HUMAN Q9UKQ9 CHEMBL3029 Kallikrein 9, Human 8 0 0 0
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 98 7 0 11

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
KLK1-1-E Kallikrein 1 (cluster #1 Of 2), Eukaryotic 47 4 1 7
KLK1-2-E Kallikrein 1 (cluster #2 Of 2), Eukaryotic 15 0 0 0
Uniprot Swissprot Chembl Description Number Shared
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 55
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 49
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 39
TPA_HUMAN P00750 CHEMBL1873 Tissue-type Plasminogen Activator, Human 33
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 33
THRB_RAT P18292 CHEMBL3078 Thrombin, Rat 27
TRYP_PIG P00761 CHEMBL2366 Trypsin, Pig 27
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 15
KLK10_HUMAN O43240 CHEMBL4180 Kallikrein 10, Human 8
KLK11_HUMAN Q9UBX7 CHEMBL3031 Kallikrein 11, Human 8
KLK12_HUMAN Q9UKR0 CHEMBL4943 Kallikrein 12, Human 8
KLK13_HUMAN Q9UKR3 CHEMBL4863 Kallikrein 13, Human 8
KLK14_HUMAN Q9P0G3 CHEMBL2641 Kallikrein 14, Human 8
KLK15_HUMAN Q9H2R5 CHEMBL2174 Kallikrein 15, Human 8
KLK2_HUMAN P20151 CHEMBL2442 Kallikrein 2, Human 8
KLK3_HUMAN P07288 CHEMBL2099 Prostate Specific Antigen, Human 8
KLK4_HUMAN Q9Y5K2 CHEMBL4446 Kallikrein 4, Human 8
KLK5_HUMAN Q9Y337 CHEMBL4447 Kallikrein 5, Human 8
KLK6_HUMAN Q92876 CHEMBL4448 Kallikrein 6, Human 8
KLK7_HUMAN P49862 CHEMBL2443 Kallikrein 7, Human 8
KLK8_HUMAN O60259 CHEMBL4812 Kallikrein 8, Human 8
KLK9_HUMAN Q9UKQ9 CHEMBL3029 Kallikrein 9, Human 8
C1R_HUMAN P00736 CHEMBL4611 Complement C1r, Human 3
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 3
PLMN_RAT Q01177 CHEMBL3204 Plasminogen, Rat 3
APOH_HUMAN P02749 CHEMBL2859 Apolipoprotein H, Human 2
C1S_HUMAN P09871 CHEMBL3913 Complement C1s, Human 2
FA9_HUMAN P00740 CHEMBL2016 Coagulation Factor IX, Human 1
PROC_HUMAN P04070 CHEMBL4444 Vitamin K-dependent Protein C, Human 1
TRY1_BOVIN P00760 CHEMBL3769 Trypsin I, Bovin 1
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 1