UCSF

Thrombin, Bovin (316 Compounds)

Swissprot:
THRB_BOVIN
Stitch:
THRB_BOVIN
UniProt:
P00735
ChEMBL:
CHEMBL4471
Reactome:
REACT_208597
REACT_220023
REACT_209521
REACT_212120
REACT_206454
REACT_219025
REACT_217199
REACT_206584
REACT_216886
REACT_215912
REACT_216819
PDB:
1A0H (DOCK)
1AVG (DOCK)
1BBR (DOCK)
1ETR (DOCK)
1ETS (DOCK)
1ETT (DOCK)
1HRT (DOCK)
1ID5 (DOCK)
1MKW (DOCK)
1MKX (DOCK)
1NL1 (DOCK)
1NL2 (DOCK)
1TBQ (DOCK)
1TBR (DOCK)
1TOC (DOCK)
1UCY (DOCK)
1UVT (DOCK)
1UVU (DOCK)
1VIT (DOCK)
1YCP (DOCK)
2A1D (DOCK)
2HPP (DOCK)
2ODY (DOCK)
2PF1 (DOCK)
2PF2 (DOCK)
2SPT (DOCK)
3PMA (DOCK)
3PMB (DOCK)
F2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 316 6 4 9
Binding ≤ 1μM 235 5 4 6
Functional ≤ 10μM 0 0 0 0
Uniprot Swissprot Chembl Description Number Shared
FA10_BOVIN P00743 CHEMBL3656 Coagulation Factor X, Bovin 51

Gamma-carboxylation of protein precursors

Uniprot Swissprot Chembl Description Number Shared
FA10_BOVIN P00743 CHEMBL3656 Coagulation Factor X, Bovin 51

Intrinsic Pathway

Uniprot Swissprot Chembl Description Number Shared
FA10_BOVIN P00743 CHEMBL3656 Coagulation Factor X, Bovin 51

Removal of aminoterminal propeptides from gamma-carboxylated proteins

Uniprot Swissprot Chembl Description Number Shared
FA10_BOVIN P00743 CHEMBL3656 Coagulation Factor X, Bovin 51

Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu

Uniprot Swissprot Chembl Description Number Shared
FA10_BOVIN P00743 CHEMBL3656 Coagulation Factor X, Bovin 51
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 4,156 65 14 68
THRB_MOUSE P19221 CHEMBL1075308 Prothrombin, Mouse 2 0 0 0
THRB_RAT P18292 CHEMBL3078 Thrombin, Rat 64 3 2 7

Clustered By Gene (0)

Clustered By Organism (7)

Code Description Substances Purchasable Natural In Man
THRB-1-E Prothrombin (cluster #1 Of 8), Eukaryotic 3,647 18 8 54
THRB-2-E Prothrombin (cluster #2 Of 8), Eukaryotic 47 0 0 0
THRB-3-E Prothrombin (cluster #3 Of 8), Eukaryotic 7 1 0 0
THRB-4-E Prothrombin (cluster #4 Of 8), Eukaryotic 527 6 2 13
THRB-5-E Prothrombin (cluster #5 Of 8), Eukaryotic 40 7 3 7
THRB-6-E Prothrombin (cluster #6 Of 8), Eukaryotic 9 1 0 0
THRB-7-E Prothrombin (cluster #7 Of 8), Eukaryotic 4 0 0 0
THRB-8-E Prothrombin (cluster #8 Of 8), Eukaryotic 285 35 3 4
Uniprot Swissprot Chembl Description Number Shared
TRY1_BOVIN P00760 CHEMBL3769 Trypsin I, Bovin 80
TRY2_BOVIN Q29463 CHEMBL4472 Trypsin II, Bovin 66
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 59
FA10_BOVIN P00743 CHEMBL3656 Coagulation Factor X, Bovin 51
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 25
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 17
TPA_HUMAN P00750 CHEMBL1873 Tissue-type Plasminogen Activator, Human 14
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 11
CATB_BOVIN P07688 CHEMBL2323 Cathepsin B, Bovin 8
PLMN_BOVIN P06868 CHEMBL2957 Plasminogen, Bovin 8
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 7
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 3
THRB_RAT P18292 CHEMBL3078 Thrombin, Rat 3
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 3
TRY3_HUMAN P35030 CHEMBL4551 Trypsin III, Human 2
ANT3_HUMAN P01008 CHEMBL1950 Antithrombin-III Precursor, Human 1
TRYB1_HUMAN Q15661 CHEMBL2617 Tryptase Beta-1, Human 1