UCSF
Image of Isoindolin-1-one

Identity 99% 90% 80% 70% Substructure

Isoindolin-1-one

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
2 1 10 8 1 1 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 3 2,033 92 12 2 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
MDM2_HUMAN Q00987 CHEMBL5023 P53-binding Protein Mdm-2, Human 36 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
MDM2_HUMAN Q00987 CHEMBL5023 P53-binding Protein Mdm-2, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RENI_HUMAN P00797 CHEMBL286 Renin, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RENI_HUMAN P00797 CHEMBL286 Renin, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104305 Z104305 CHEMBL1907611 Tumour Suppressor P53/oncoprotein Mdm2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
E2QDN0_ECOLX E2QDN0 CHEMBL1795153 Thymidylate Synthase (EC 2.1.1.45) (TS) (TSase), Ecolx 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
E2QDN0_ECOLX E2QDN0 CHEMBL1795153 Thymidylate Synthase (EC 2.1.1.45) (TS) (TSase), Ecolx 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase