UCSF

Smoothened Homolog, Human (305 Compounds)

Swissprot:
SMO_HUMAN
Stitch:
SMO_HUMAN
UniProt:
Q99835
ChEMBL:
CHEMBL5971
Reactome:
REACT_18372
PDB:
SMO

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 305 11 1 0
Binding ≤ 1μM 241 7 1 0
Functional ≤ 10μM 141 5 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_18372 Class B/2 (Secretin family receptors) Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SMO_MOUSE P56726 CHEMBL6080 Smoothened Homolog, Mouse 70 6 1 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
SMO_MOUSE P56726 CHEMBL6080 Smoothened Homolog, Mouse 57
SHH_MOUSE Q62226 CHEMBL5387 Sonic Hedgehog Protein, Mouse 45
MTP_HUMAN P55157 CHEMBL2569 Microsomal Triglyceride Transfer Protein Large Subunit, Human 9
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 5
APOB_HUMAN P04114 CHEMBL4549 Apolipoprotein B-100, Human 3
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 2
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 2
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 2
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 2
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1