UCSF

Alpha-2a Adrenergic Receptor, Mouse (4 Compounds)

Swissprot:
ADA2A_MOUSE
Stitch:
ADA2A_MOUSE
UniProt:
Q01338
ChEMBL:
CHEMBL4075
Reactome:
REACT_256826
REACT_250590
REACT_255413
REACT_250376
REACT_258013
PDB:
Adra2a

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 4 4 4 3
Binding ≤ 1μM 4 4 4 3

Reactome Network (5)

Reactome ID Description Species
REACT_256826 Adrenaline signalling through Alpha-2 adrenergic receptor Mus musculus
REACT_250590 Adrenaline,noradrenaline inhibits insulin secretion Mus musculus
REACT_255413 Adrenoceptors Mus musculus
REACT_250376 G alpha (i) signalling events Mus musculus
REACT_258013 G alpha (z) signalling events Mus musculus
Uniprot Swissprot Chembl Description Number Shared
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 4

Adrenaline,noradrenaline inhibits insulin secretion

Uniprot Swissprot Chembl Description Number Shared
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 4

Adrenoceptors

Uniprot Swissprot Chembl Description Number Shared
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 4

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 4

G alpha (z) signalling events

Uniprot Swissprot Chembl Description Number Shared
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 228 41 13 13
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 690 104 52 54
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 3 3 3 3
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1,202 187 86 87

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
ADA2A-1-E Alpha-2a Adrenergic Receptor (cluster #1 Of 4), Eukaryotic 1,558 143 70 74
ADA2A-2-E Alpha-2a Adrenergic Receptor (cluster #2 Of 4), Eukaryotic 134 35 9 13
ADA2A-3-E Alpha-2a Adrenergic Receptor (cluster #3 Of 4), Eukaryotic 273 101 40 31
ADA2A-4-E Alpha-2a Adrenergic Receptor (cluster #4 Of 4), Eukaryotic 98 9 3 3
Uniprot Swissprot Chembl Description Number Shared
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 4
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 4
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 4
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 4
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 4
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 4
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 4
ADA2B_MOUSE P30545 CHEMBL2405 Alpha-2b Adrenergic Receptor, Mouse 4
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 4
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 4
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 4
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 4
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 4
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 3
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 3
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 3
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 2
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 2
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 2
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
ADA2B_BOVIN O77700 CHEMBL3523 Alpha-2b Adrenergic Receptor, Bovin 2
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 2
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 1
NISCH_HUMAN Q9Y2I1 CHEMBL3923 Nischarin, Human 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
S22A1_HUMAN O15245 CHEMBL5685 Solute Carrier Family 22 Member 1, Human 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1