UCSF

Nucleophosmin, Human (11 Compounds)

Swissprot:
NPM_HUMAN
Stitch:
NPM_HUMAN
UniProt:
P06748
ChEMBL:
CHEMBL5178
Reactome:
REACT_22186
REACT_9395
PDB:
2P1B (DOCK)
2VXD (DOCK)
NPM1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 11 2 1 2
Binding ≤ 1μM 10 1 1 1
Functional ≤ 10μM 3 0 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_22186 Deposition of new CENPA-containing nucleosomes at the centromere Homo sapiens
REACT_9395 Nuclear import of Rev protein Homo sapiens

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 14
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 9
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 4
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 4
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 3
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 2
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 2
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 1
ABL2_MOUSE Q4JIM5 CHEMBL5222 Tyrosine-protein Kinase ABL2, Mouse 1
ABL_MLVAB P00521 CHEMBL5166 Tyrosine-protein Kinase V-ABL, Mlvab 1
ACK1_HUMAN Q07912 CHEMBL4599 Tyrosine Kinase Non-receptor Protein 2, Human 1
BLK_MOUSE P16277 CHEMBL3343 Tyrosine-protein Kinase BLK, Mouse 1
BMX_HUMAN P51813 CHEMBL3834 Tyrosine-protein Kinase BMX, Human 1
BTK_HUMAN Q06187 CHEMBL5251 Tyrosine-protein Kinase BTK, Human 1
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
EPHB2_HUMAN P29323 CHEMBL3290 Ephrin Type-B Receptor 2, Human 1
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 1
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FER_HUMAN P16591 CHEMBL3982 Tyrosine-protein Kinase FER, Human 1
FES_HUMAN P07332 CHEMBL5455 Tyrosine-protein Kinase FES, Human 1
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 1
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 1
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 1
IRAK4_HUMAN Q9NWZ3 CHEMBL3778 Interleukin-1 Receptor-associated Kinase 4, Human 1
KCC1D_HUMAN Q8IU85 CHEMBL5073 CaM Kinase I Delta, Human 1
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 1
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 1
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
M4K2_HUMAN Q12851 CHEMBL5330 Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, Human 1
M4K5_HUMAN Q9Y4K4 CHEMBL4852 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 1
MINK1_HUMAN Q8N4C8 CHEMBL5518 Misshapen-like Kinase 1, Human 1
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 1
NTRK2_HUMAN Q16620 CHEMBL4898 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 1
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 1
STK24_HUMAN Q9Y6E0 CHEMBL5082 Serine/threonine-protein Kinase 24, Human 1
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein Kinase MST1, Human 1
TBK1_HUMAN Q9UHD2 CHEMBL5408 Serine/threonine-protein Kinase TBK1, Human 1
TEC_HUMAN P42680 CHEMBL4246 Tyrosine-protein Kinase TEC, Human 1
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 1
TXK_HUMAN P42681 CHEMBL4367 Tyrosine-protein Kinase TXK, Human 1
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 1
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 1
Z80036 Z80036 CHEMBL614524 BaF3 (IL-3-dependent Pro-B-cells) 1