UCSF

PI3-kinase P85-beta Subunit, Human (47 Compounds)

Swissprot:
P85B_HUMAN
Stitch:
P85B_HUMAN
UniProt:
O00459
ChEMBL:
CHEMBL4437
Reactome:
REACT_19358
REACT_147727
REACT_19344
REACT_147814
REACT_17025
REACT_12555
REACT_18407
REACT_18283
REACT_1695
REACT_23891
REACT_23837
REACT_115529
REACT_23832
REACT_976
REACT_12464
REACT_75829
REACT_23787
REACT_11051
REACT_163769
REACT_160158
REACT_111040
REACT_121025
REACT_12621
REACT_228166
PDB:
2KT1 (DOCK)
2XS6 (DOCK)
3MTT (DOCK)
3O5Z (DOCK)
PIK3R2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 47 5 3 2
Binding ≤ 1μM 26 3 1 1
Functional ≤ 10μM 0 0 0 0

Reactome Network (24)

Reactome ID Description Species
REACT_19358 CD28 dependent PI3K/Akt signaling Homo sapiens
REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Homo sapiens
REACT_19344 Costimulation by the CD28 family Homo sapiens
REACT_147814 DAP12 signaling Homo sapiens
REACT_17025 Downstream signal transduction Homo sapiens
REACT_12555 Downstream TCR signaling Homo sapiens
REACT_18407 G alpha (12/13) signalling events Homo sapiens
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_1695 GPVI-mediated activation cascade Homo sapiens
REACT_23891 Interleukin receptor SHC signaling Homo sapiens
REACT_23837 Interleukin-3, 5 and GM-CSF signaling Homo sapiens
REACT_115529 Interleukin-7 signaling Homo sapiens
REACT_23832 Nephrin interactions Homo sapiens
REACT_976 PI3K Cascade Homo sapiens
REACT_12464 PI3K/AKT activation Homo sapiens
REACT_75829 PIP3 activates AKT signaling Homo sapiens
REACT_23787 Regulation of signaling by CBL Homo sapiens
REACT_11051 Rho GTPase cycle Homo sapiens
REACT_163769 Role of LAT2/NTAL/LAB on calcium mobilization Homo sapiens
REACT_160158 Role of phospholipids in phagocytosis Homo sapiens
REACT_111040 Signaling by SCF-KIT Homo sapiens
REACT_121025 Synthesis of PIPs at the plasma membrane Homo sapiens
REACT_12621 Tie2 Signaling Homo sapiens
REACT_228166 VEGFA-VEGFR2 Pathway Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 2
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 2
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 2
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 2
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14

Constitutive PI3K/AKT Signaling in Cancer

Uniprot Swissprot Chembl Description Number Shared
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 2
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 2
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 2
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 2
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 14

Costimulation by the CD28 family

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14

DAP12 signaling

Uniprot Swissprot Chembl Description Number Shared
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PLCG1_HUMAN P19174 CHEMBL3964 Phospholipase C-gamma-1, Human 1
PLCG2_HUMAN P16885 CHEMBL4100 Phospholipase C-gamma-2, Human 3

Downstream signal transduction

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PLCG1_HUMAN P19174 CHEMBL3964 Phospholipase C-gamma-1, Human 1

Downstream TCR signaling

Uniprot Swissprot Chembl Description Number Shared
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14

G alpha (12/13) signalling events

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14

G alpha (q) signalling events

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14

GPVI-mediated activation cascade

Uniprot Swissprot Chembl Description Number Shared
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 2
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 2
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 2
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 14
PLCG2_HUMAN P16885 CHEMBL4100 Phospholipase C-gamma-2, Human 3

Interleukin receptor SHC signaling

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 14

Interleukin-3, 5 and GM-CSF signaling

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 14

Interleukin-7 signaling

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37

Nephrin interactions

Uniprot Swissprot Chembl Description Number Shared
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14

PI3K Cascade

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14

PI3K/AKT activation

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14

PIP3 activates AKT signaling

Uniprot Swissprot Chembl Description Number Shared
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 2
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 2
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 2
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 2
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 14

Regulation of signaling by CBL

Uniprot Swissprot Chembl Description Number Shared
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 14

Role of LAT2/NTAL/LAB on calcium mobilization

Uniprot Swissprot Chembl Description Number Shared
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14

Role of phospholipids in phagocytosis

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PLCG1_HUMAN P19174 CHEMBL3964 Phospholipase C-gamma-1, Human 1
PLCG2_HUMAN P16885 CHEMBL4100 Phospholipase C-gamma-2, Human 3

Signaling by SCF-KIT

Uniprot Swissprot Chembl Description Number Shared
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14

Synthesis of PIPs at the plasma membrane

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 14
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 14

Tie2 Signaling

Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14

VEGFA-VEGFR2 Pathway

Uniprot Swissprot Chembl Description Number Shared
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
P85B-1-E PI3-kinase P85-beta Subunit (cluster #1 Of 2), Eukaryotic 11 0 0 0
P85B-2-E PI3-kinase P85-beta Subunit (cluster #2 Of 2), Eukaryotic 36 5 3 2
Uniprot Swissprot Chembl Description Number Shared
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 37
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 14
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 14
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 14
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 14
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 7
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
GRB2_HUMAN P62993 CHEMBL3663 Growth Factor Receptor-bound Protein 2, Human 4
PK3CA_BOVIN P32871 CHEMBL2498 PI3-kinase P110-alpha Subunit, Bovin 4
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 3
PLCG2_HUMAN P16885 CHEMBL4100 Phospholipase C-gamma-2, Human 3
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 2
AKT2_HUMAN P31751 CHEMBL2431 Serine/threonine-protein Kinase AKT2, Human 2
AKT3_HUMAN Q9Y243 CHEMBL4816 Serine/threonine-protein Kinase AKT3, Human 2
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 2
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 2
5NTD_RAT P21588 CHEMBL1075214 5'-nucleotidase, Rat 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 1
AK1A1_RAT P51635 CHEMBL3871 Aldehyde Reductase, Rat 1
AK1CL_MOUSE Q91WR5 CHEMBL1075270 Aldo-keto Reductase Family 1 Member C21, Mouse 1
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 1
AMPH_ECOLI P0AD70 CHEMBL4413 Penicillin-binding Protein AmpH, Ecoli 1
AOFA_BOVIN P21398 CHEMBL3254 Monoamine Oxidase A, Bovin 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 1
CAH13_MOUSE Q9D6N1 CHEMBL2186 Carbonic Anhydrase XIII, Mouse 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 1
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 1
DHB2_HUMAN P37059 CHEMBL2789 Estradiol 17-beta-dehydrogenase 2, Human 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
LGUL_HUMAN Q04760 CHEMBL2424 Glyoxalase I, Human 1
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 1
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 1
LOX15_RABIT P12530 CHEMBL4358 Arachidonate 15-lipoxygenase, Rabit 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 1
MDH_THETH P10584 CHEMBL4255 Malate Dehydrogenase, Theth 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
MYLK_CHICK P11799 CHEMBL3062 Myosin Light Chain Kinase, Smooth Muscle, Chick 1
MYLK_HUMAN Q15746 CHEMBL2428 Myosin Light Chain Kinase, Smooth Muscle, Human 1
NANH_CLOPE P10481 CHEMBL5189 Sialidase, Clope 1
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 1
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 1
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 1
PLCG1_HUMAN P19174 CHEMBL3964 Phospholipase C-gamma-1, Human 1
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 1
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 1
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 1
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 1
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 1
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 1
R1AB_CVHSA P0C6X7 CHEMBL5118 Replicase Polyprotein 1ab, Cvhsa 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 1
XDH_BOVIN P80457 CHEMBL3649 Xanthine Dehydrogenase, Bovin 1
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 1