UCSF

Xanthine Dehydrogenase, Bovin (81 Compounds)

Swissprot:
XDH_BOVIN
Stitch:
XDH_BOVIN
UniProt:
P80457
ChEMBL:
CHEMBL3649
PDB:
1FIQ (DOCK)
1FO4 (DOCK)
1N5X (DOCK)
1V97 (DOCK)
1VDV (DOCK)
3AM9 (DOCK)
3AMZ (DOCK)
3B9J (DOCK)
3BDJ (DOCK)
3ETR (DOCK)
3EUB (DOCK)
3NRZ (DOCK)
3NS1 (DOCK)
3NVV (DOCK)
3NVW (DOCK)
3NVY (DOCK)
3NVZ (DOCK)
3SR6 (DOCK)
XDH

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 81 17 9 7
Binding ≤ 1μM 51 9 5 4

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 37 17 14 7
XDH_RAT P22985 CHEMBL1075246 Xanthine Dehydrogenase/oxidase, Rat 16 2 1 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
XDH-1-E Xanthine Dehydrogenase (cluster #1 Of 2), Eukaryotic 59 12 3 3
XDH-2-E Xanthine Dehydrogenase (cluster #2 Of 2), Eukaryotic 61 18 16 8
Uniprot Swissprot Chembl Description Number Shared
XDH_RAT P22985 CHEMBL1075246 Xanthine Dehydrogenase/oxidase, Rat 10
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 4
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 3
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 2
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 2
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 2
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 2
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 2
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 2
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 2
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 2
LGUL_HUMAN Q04760 CHEMBL2424 Glyoxalase I, Human 2
LOX12_HUMAN P18054 CHEMBL3687 Arachidonate 12-lipoxygenase, Human 2
LOX15_HUMAN P16050 CHEMBL2903 Arachidonate 15-lipoxygenase, Human 2
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 2
NANH_CLOPE P10481 CHEMBL5189 Sialidase, Clope 2
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 2
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 2
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 2
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 2
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 2
5NTD_RAT P21588 CHEMBL1075214 5'-nucleotidase, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
AK1A1_RAT P51635 CHEMBL3871 Aldehyde Reductase, Rat 1
AK1CL_MOUSE Q91WR5 CHEMBL1075270 Aldo-keto Reductase Family 1 Member C21, Mouse 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 1
AMPH_ECOLI P0AD70 CHEMBL4413 Penicillin-binding Protein AmpH, Ecoli 1
AOFA_BOVIN P21398 CHEMBL3254 Monoamine Oxidase A, Bovin 1
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 1
CAH13_MOUSE Q9D6N1 CHEMBL2186 Carbonic Anhydrase XIII, Mouse 1
CAH14_HUMAN Q9ULX7 CHEMBL3510 Carbonic Anhydrase XIV, Human 1
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH3_HUMAN P07451 CHEMBL2885 Carbonic Anhydrase III, Human 1
CAH4_HUMAN P22748 CHEMBL3729 Carbonic Anhydrase IV, Human 1
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 1
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 1
CAH7_HUMAN P43166 CHEMBL2326 Carbonic Anhydrase VII, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CD38_HUMAN P28907 CHEMBL4660 Lymphocyte Differentiation Antigen CD38, Human 1
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 1
DHB2_HUMAN P37059 CHEMBL2789 Estradiol 17-beta-dehydrogenase 2, Human 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DYR_MOUSE P00375 CHEMBL4564 Dihydrofolate Reductase, Mouse 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
FABI_ECOLI P0AEK4 CHEMBL1857 Enoyl-[acyl-carrier-protein] Reductase, Ecoli 1
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 1
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 1
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 1
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 1
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 1
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 1
KD4DL_HUMAN B2RXH2 CHEMBL1293226 Lysine-specific Demethylase 4D-like, Human 1
LOX15_RABIT P12530 CHEMBL4358 Arachidonate 15-lipoxygenase, Rabit 1
LOX1_SOYBN P08170 CHEMBL4586 Seed Lipoxygenase-1, Soybn 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase, Rat 1
LX12L_RAT Q02759 CHEMBL2741 Arachidonate 12-lipoxygenase, Rat 1
LX15B_RAT Q8K4F2 CHEMBL3289 Arachidonate 15-lipoxygenase, Type II, Rat 1
MDH_THETH P10584 CHEMBL4255 Malate Dehydrogenase, Theth 1
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 1
P85B_HUMAN O00459 CHEMBL4437 PI3-kinase P85-beta Subunit, Human 1
PA21B_HUMAN P04054 CHEMBL4426 Phospholipase A2 Group 1B, Human 1
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 1
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 1
R1AB_CVHSA P0C6X7 CHEMBL5118 Replicase Polyprotein 1ab, Cvhsa 1
TOP1_RAT Q9WUL0 CHEMBL1075164 DNA Topoisomerase 1, Rat 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 1
TYSY_LACCA P00469 CHEMBL5328 Thymidylate Synthase, Lacca 1
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 1

Most Common Rings